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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">111</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2015-14-3-48-54</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ACUTE LEUKEMIA</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОСТРЫЙ ЛЕЙКОЗ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Diagnosis and treatment of acute myeloid leukemia in children: Modern aspects</article-title><trans-title-group xml:lang="ru"><trans-title>Современные аспекты диагностики и лечения острого миелоидного лейкоза у детей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Barovskaya</surname><given-names>Yu. A.</given-names></name><name xml:lang="ru"><surname>Баровская</surname><given-names>Ю. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ju1ia@tut.by</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Republican Center of Pediatric Oncology, Hematology, and Immunology</institution></aff><aff><institution xml:lang="ru">Республиканский научно-практический центр детской онкологии, гематологии и иммунологии Минздрава Республики Беларусь</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-09-19" publication-format="electronic"><day>19</day><month>09</month><year>2015</year></pub-date><volume>14</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>48</fpage><lpage>54</lpage><history><date date-type="received" iso-8601-date="2018-09-19"><day>19</day><month>09</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/111">https://hemoncim.com/jour/article/view/111</self-uri><abstract xml:lang="en"><p>Acute myeloid leukemia (AML) in children is presented by an extremely heterogeneous group of diseases; for this reason, optimization of methods for its therapy is a difficult task. This review of literature presents modern concepts of the prognostic factors, based on the genetic changes in tumor cells, and the modern potentialities of therapy for AML.</p></abstract><trans-abstract xml:lang="ru"><p>Острый миелоидный лейкоз (ОМЛ) у детей представлен крайне гетерогенной группой заболеваний, в связи с этим оптимизация методов лечения данной патологии является трудной задачей. В статье, представляющей собой обзор литературы, описаны современные представления о факторах прогноза, основанных на генетических изменениях в опухолевых клетках, а также существующие на сегодняшний день возможности терапии ОМЛ.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>острый миелоидный лейкоз</kwd><kwd>диагностика</kwd><kwd>генетические аномалии</kwd><kwd>факторы прогноза</kwd><kwd>лечение</kwd><kwd>иммунотерапия</kwd><kwd>children</kwd><kwd>acute myeloid leukemia</kwd><kwd>diagnosis</kwd><kwd>genetic abnormalities</kwd><kwd>prognostic factors</kwd><kwd>therapy</kwd><kwd>immunotherapy</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Петрович СВ, Алейникова ОВ, Шумихина ТП, Чуниховский СП, Федорова ЛЮ, Сахарова ОГидр. Эпидемиологические аспекты онкогематологических забо- леваний у детей в Республике Беларусь. 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