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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">117</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2015-14-4-10-16</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PALLIATIVE CARE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ПАЛЛИАТИВНАЯ ПОМОЩЬ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Management of chronic (persistent) pain syndrome in children</article-title><trans-title-group xml:lang="ru"><trans-title>Лечение хронического (персистирующего) болевого синдрома у детей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kumirova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Кумирова</surname><given-names>Элла Вячеславовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>k_ella2004@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal Research Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry Rogachev</institution></aff><aff><institution xml:lang="ru">Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Children’s Palliative Care Foundation</institution></aff><aff><institution xml:lang="ru">Благотворительный фонд развития паллиативной помощи «Детский паллиатив»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-12-19" publication-format="electronic"><day>19</day><month>12</month><year>2015</year></pub-date><volume>14</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>10</fpage><lpage>16</lpage><history><date date-type="received" iso-8601-date="2018-09-19"><day>19</day><month>09</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/117">https://hemoncim.com/jour/article/view/117</self-uri><abstract xml:lang="en"><p>Based on the international practice and recommendations, the author discusses the problems in management of chronic (persistent) pain syndrome and describes the use of analgesics - opioid and non-opioid - in children. Analgesics and their forms registered in Russian Federation, available for children, are listed.</p></abstract><trans-abstract xml:lang="ru"><p>В статье освещаются вопросы лечения хронического (персистирующего) болевого синдрома у детей, описаны особенности использования анальгетиков у детей как наркотических, так и ненаркотических, на основе международной практики и рекомендаций. Приводятся доступные для использования у детей обезболивающие препараты и их формы, зарегистрированные в РФ.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>хроническая (персистирующая) боль</kwd><kwd>наркотические анальгетики</kwd><kwd>морфин короткого и пролонгированного действия</kwd><kwd>children</kwd><kwd>chronic (persistent) pain</kwd><kwd>opioid analgesics</kwd><kwd>short-acting and long-acting morphine</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses. WHO; 2012. Available at: http://apps.who.int/iris/bitstream/10665/44540/1/9789241548120_Guidelines.pdf</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Hain R, Jassal SS. Paediatric palliative medicine. Oxford specialist handbooks in paediatrics. 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