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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">142</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2016-15-1-8-9</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>EDITORIAL</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>РЕДАКЦИОННАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Primary immunodeficiencies: Realities of the 21<sup>st</sup> century</article-title><trans-title-group xml:lang="ru"><trans-title>Первичные иммунодефициты -реалии XXI века</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shcherbina</surname><given-names>Anna Yu.</given-names></name><name xml:lang="ru"><surname>Щербина</surname><given-names>Анна Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shcher26@hotmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal Research Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry Rogachev</institution></aff><aff><institution xml:lang="ru">Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-03-19" publication-format="electronic"><day>19</day><month>03</month><year>2016</year></pub-date><volume>15</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>8</fpage><lpage>9</lpage><history><date date-type="received" iso-8601-date="2018-09-19"><day>19</day><month>09</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/142">https://hemoncim.com/jour/article/view/142</self-uri><abstract xml:lang="ru"><p/></abstract></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Schultz W. Über eigenartige Halserkrankungen (a) Monozytenangina, (b) gangrä-nisierende Prozesse und Defekte des Granulozytensystem. Dtsch Med Wochenschr. 1922;48:1495-7.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Syllaba L, Henner K. Contibution à l’indépendence de l’athetose double idiopathique et congénitale: atteinte familiale, syndrome dystrophique, signe du réseau vasculaire conjonctival, intégrité psychique. 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