Pediatric Hematology/Oncology and ImmunopathologyPediatric Hematology/Oncology and ImmunopathologyВопросы гематологии/онкологии и иммунопатологии в педиатрии1726-17082414-9314Fund Doctors, Innovations, Science for Children1610.24287/1726-1708-2017-16-4-107-112СтатьиTelomere length and children’s healthДлина теломер и здоровье детейhttps://orcid.org/0000-0001-9002-7909KagirovaZ. R.КагироваЗ.Р.
Russian Federation
https://orcid.org/0000-0002-4317-2094DeminaI. A.ДёминаИ.А.
Russian Federation

PhD, leading scientist Laboratory of cell’s immunology and immunogenesis

Russia 117997, Moscow, Samory Mashela st., 1+7 (495) 287-6570, ext. 5615

idemina@mail.ruBlokhinB. M.БлохинБ.М.
Russian Federation
https://orcid.org/0000-0002-1643-5960RumyantsevA. G.РумянцевА. Г.
Russian Federation
Pirogov Russian National Research Medical UniversityФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РоссииDmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, ImmunologyФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России0911201716410711209082018Copyright ©; 2017, «D. Rogachev NMRCPHOI»Copyright ©; 2017, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России2017«D. Rogachev NMRCPHOI»ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава Россииhttps://creativecommons.org/licenses/by/4.0https://hemoncim.com/jour/article/view/16

In the review of the literature, the authors described in detail modern concepts of the structure and functions of telomeres, telomerase and shelterin complexes. The article contains an overview of the data and published to date the results of a study of telomere length in healthy children of different ages, the relationship between body length and certain diseases, as well as the influence of a number physiological factors on the length of children telomere.

В обзоре литературы авторы подробно описали современные представления о структуре и функции теломер, теломеразного и шелтеринового комплексов. Статья содержит обзор данных и опубликованных к настоящему времени результатов исследования длины теломер у здоровых детей разного возраста, связь длины теломер и некоторых заболеваний, а также влияния ряда физиологических факторов на длину теломер у детей.

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