<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">177</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2018-17-2-69-75</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Donor-related factors affecting the outcome of hematopoietic stem cell transplantations in children</article-title><trans-title-group xml:lang="ru"><trans-title>Анализ факторов, связанных с неродственным донором гемопоэтических стволовых клеток, влияющих на результаты аллогенных трансплантаций у детей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3797-5808</contrib-id><name-alternatives><name xml:lang="en"><surname>Sidorova</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Сидорова</surname><given-names>Н.В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Department of stem cell transplantation</p><p>Russia, 119571, Moscow, Leninsky prospect, 117</p></bio><email>Valerevna25@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4569-657X</contrib-id><name-alternatives><name xml:lang="en"><surname>Pristanskova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Пристанскова</surname><given-names>Е.А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2945-284X</contrib-id><name-alternatives><name xml:lang="en"><surname>Kirgizov</surname><given-names>K. I.</given-names></name><name xml:lang="ru"><surname>Киргизов</surname><given-names>К.И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2652-8642</contrib-id><name-alternatives><name xml:lang="en"><surname>Konstantinova</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Константинова</surname><given-names>В.В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4170-7152</contrib-id><name-alternatives><name xml:lang="en"><surname>Burya</surname><given-names>A. E.</given-names></name><name xml:lang="ru"><surname>Буря</surname><given-names>А.Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1587-3256</contrib-id><name-alternatives><name xml:lang="en"><surname>Blagonravova</surname><given-names>O. L.</given-names></name><name xml:lang="ru"><surname>Благонравова</surname><given-names>О.Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4496-1156</contrib-id><name-alternatives><name xml:lang="en"><surname>Persiantseva</surname><given-names>M. I.</given-names></name><name xml:lang="ru"><surname>Персианцева</surname><given-names>М.И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2021-0465</contrib-id><name-alternatives><name xml:lang="en"><surname>Slinin</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Слинин</surname><given-names>А.С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4431-1444</contrib-id><name-alternatives><name xml:lang="en"><surname>Skorobogatova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Скоробогатова</surname><given-names>Е.В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The Russian Children's Research Hospital, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБУ «Российская детская клиническая больница» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-09-20" publication-format="electronic"><day>20</day><month>09</month><year>2018</year></pub-date><volume>17</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>69</fpage><lpage>75</lpage><history><date date-type="received" iso-8601-date="2018-09-20"><day>20</day><month>09</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1970, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1970, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>1970</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/177">https://hemoncim.com/jour/article/view/177</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>Allogeneic hematopoietic stem cell transplantation</kwd><kwd>matched unrelated donor</kwd><kwd>mismatched unrelated donor</kwd><kwd>relapse-free survival in leukemia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>аллогенная трансплантация гемопоэтических стволовых клеток</kwd><kwd>совместимый неродственный донор</kwd><kwd>не полностью совместимый неродственный донор</kwd><kwd>безрецидивная выживаемость при лейкозах</kwd><kwd>реакция «трансплантат против хозяина»</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Скоробогатова Е.В., Балашов Д.Н., Тра-хтман П.Е., Масчан А.А., Румянцев А.Г., Киргизов К.И. Итоги двадцатилетнего опыта трансплан-тации гемопоэтических стволовых клеток у детей. Педиатрия, 2011; 90 (4): 12-6.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Афанасьев Б.В., Зубаровская Л.С., Моисеев И.С. Аллогенная трансплантация гемопоэтических стволовых клеток у детей: настоящее, проблемы, перспективы. Российскийжурналдетскойгематологииионкологии 2015; 2 (2): 28-42.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Schäfer S.H., Finke J. Mismatched unrelated alternative donors for hematological malignancies. Semin Hematol 2016; 53 (2): 77-81.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>АлянскийА.Л., МакаренкоО.А., Ива-новаН.Е., ГоловачёваА.А., КузьмичЕ.В., КучерМ.А., БабенкоЕ.В. идр. Развитие регистра неродственных доноров костного мозга в Российской Федерации: опыт НИИ детской онкологии, гематологии и трансплантологии им. Р.М. Горбачeвой. Российский журнал детской гематологии и онкологии, 2016; 3(2): 68-74.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>PasswegJ.R., BaldomeroH., PetersC., GasparH.B., CesaroS., DregerP., DuarteR.F., etal. Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation. Bone Marrow Transplant, 2014; 49 (6): 744-50.</mixed-citation></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Lown R.N., Shaw B.E. Beating the odds: factors implicated in the speed and availability of unrelated haematopoietic cell donor provision. Bone Marrow Transplant 2013; 48 (2): 210-9.</mixed-citation><mixed-citation xml:lang="ru">Lown R.N., Shaw B.E. Beating the odds: factors implicated in the speed and availability of unrelated haematopoietic cell donor provision. Bone Marrow Transplant 2013; 48 (2): 210-9.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Foeken L.M., Green A., Hurley C.K., Marry E., Wiegand T., Oudshoorn M. Donor Registries Working Group of the World Marrow Donor Association (WMDA). Monitoring the international use of unrelated donors for transplantation: the WMDA annual reports. Bone Marrow Transplant 2010; 45: 811-8.</mixed-citation><mixed-citation xml:lang="ru">Foeken L.M., Green A., Hurley C.K., Marry E., Wiegand T., Oudshoorn M. Donor Registries Working Group of the World Marrow Donor Association (WMDA). Monitoring the international use of unrelated donors for transplantation: the WMDA annual reports. Bone Marrow Transplant 2010; 45: 811-8.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><mixed-citation>Petz L.D., Gragert L. Cord Blood: Biology, Transplantation, Banking, and Regulation. The underutilization of cord blood transplantation: extent of the problem, causes, and methods improvement Vol. 1. AABB Press 2011: 557-84.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>European Federation for Immunogenetics STANDARDS FOR HISTOCOMPATIBILITY &amp; IMMUNOGENETICS TESTING Version 7.0 Accepted by the Standards and Quality Assurance Committee on 30th May 2017 Accepted by the EFI Executive Committee on 22nd October 2017 Effective from January 1st 2018: 29-31.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Verneris M.R., Lee S.J., Ahn K.W., Wang H.L., Battiwalla M., Inamoto Y., Fernandez-Vina M.A., et al. HLA-Mismatch Is Associated With Worse Outcomes After Unrelated Donor Reduced Intensity Conditioning Hematopoietic Cell Transplantation: An Analysis From The CIBMTR. Biol Blood Marrow Transplant 2015; 21 (10): 1783-9.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Petersdorf E., Anasetti C., Martin P.J., Gooley T., Radich J., Malkki M., Woolfrey A., et al. Limits of HLA-mismatching in unrelated hematopoitic cell transplantation. Blood 2004; 104 (9): 2976-80.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Crocchiolo R., Zino E, Vago L, Oneto R., Bruno B., Pollichieni S., Sacchi N., et al. No permissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoitic stem cell transplantation. Blood 2009; 114 (7): 1437-44.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Ljungman P., Brand R., Einsele H., Frassoni F., Niederwieser D., Cordonnier C. Donor CMV serologic status and outcome of CMV-seropositive recipients after unrelated donor stem cell trans- plantation: an EBMT megafile analysis. Blood 2003; 102 (13): 2455-60.</mixed-citation></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Confer D.L., Abress L.K., Navarro W., Madrigal A. Selection of adult unrelated hematopoietic stem cell donors: beyond HLA. Biol Blood Marrow Transplant 2010; 16 (1 suppl.): S8-S11.</mixed-citation><mixed-citation xml:lang="ru">Confer D.L., Abress L.K., Navarro W., Madrigal A. Selection of adult unrelated hematopoietic stem cell donors: beyond HLA. Biol Blood Marrow Transplant 2010; 16 (1 suppl.): S8-S11.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Афанасьев Б.В., Зубаровская Л.С., Алянский А.Л., Паина О.В., Боровкова А.С., Кузьмич Е.В., Быкова Т.А. и др. Выбор донора при аллогенной трансплантации гемопоэтических стволовых клеток. Российский журнал детской гематологии и онкологии, 2016; 3 (3): 30-6.</mixed-citation><mixed-citation xml:lang="ru">Афанасьев Б.В., Зубаровская Л.С., Алянский А.Л., Паина О.В., Боровкова А.С., Кузьмич Е.В., Быкова Т.А. и др. Выбор донора при аллогенной трансплантации гемопоэтических стволовых клеток. Российский журнал детской гематологии и онкологии, 2016; 3 (3): 30-6.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><mixed-citation>Devillier R., Dalle J.-H., Kulasekararaj A., D’Aveni M., Clément L., Chybicka A., Vigouroux S., et al. Unrelated alternative donor transplantation for severe acquired aplastic anemia: a study from the French Society of Bone Marrow Transplantation and Cell Therapies and the EBMT Severe Aplastic Anemia Working Party. Haematologica 2016; 101 (7): 884-90.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Weisdorf D.J., Nelson G., Lee S.J., Haagenson M., Spellman S., Antin J.H., Bolwell B., et al. Chronic Leukemia Working Committee. Sibling versus unrelated donor allogeneic hematopoietic cell transplantation for chronic myelogenous leukemia: refined HLA matching reveals more graft-versus-host disease but not less relapse. Biol Blood Marrow Transplant 2009; 15 (11): 1475-8.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Kanda J. Effect of HLA mismatch on acute graft-versus-host disease. IntJHematol 2013, 98 (3): 300-8.</mixed-citation></ref></ref-list></back></article>
