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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">185</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2018-17-2-136-143</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Economic methods of medical technology assessment in hematology</article-title><trans-title-group xml:lang="ru"><trans-title>Экономические методы оценки эффективности медицинских технологий в гематологии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4727-0131</contrib-id><name-alternatives><name xml:lang="en"><surname>Gurkina</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Гуркина</surname><given-names>М.В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>adviser to General Director</p><p>Russia 117997, Moscow, Samory Mashela st., 1</p></bio><email>mvgurkina@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2756-7325</contrib-id><name-alternatives><name xml:lang="en"><surname>Smetanina</surname><given-names>N. S.</given-names></name><name xml:lang="ru"><surname>Сметанина</surname><given-names>Н.С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1643-5960</contrib-id><name-alternatives><name xml:lang="en"><surname>Rumyntsev</surname><given-names>A. G.</given-names></name><name xml:lang="ru"><surname>Румянцев</surname><given-names>А.Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology&#13;
Department of Hematology, Oncology and radiotherapy Russian National Research Medical University named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-09-20" publication-format="electronic"><day>20</day><month>09</month><year>2018</year></pub-date><volume>17</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>136</fpage><lpage>143</lpage><history><date date-type="received" iso-8601-date="2018-09-20"><day>20</day><month>09</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1970, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1970, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>1970</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/185">https://hemoncim.com/jour/article/view/185</self-uri><abstract xml:lang="en"><p>The use of available resources with maximum benefit to the patient is the main goal of healthcare, therefore the economic evaluation of the effectiveness of medical technologies becomes important. In this article all modern methods of pharmacoeconomic analysis are presented in detail on the example of hematological diseases. Particular attention is paid to the characteristics by which healthcare providers can assess the validity of data on the pharmacoeconomic effectiveness of medical technologies.</p></abstract><trans-abstract xml:lang="ru"><p>Использование имеющихся материальных ресурсов с максимальной пользой для пациента - главная задача здравоохранения, поэтому клинико-экономическая оценка эффективности медицинских технологий приобретает важную роль. В настоящей статье подробно, на примере гематологического заболевания, представлены все современные методы фармакоэкономического анализа. Особое внимание уделено характеристикам, по которым организаторы здравоохранения могут оценить валидность данных о фармакоэкономической эффективности медицинских технологий.</p></trans-abstract><kwd-group xml:lang="en"><kwd>economic evaluation</kwd><kwd>pharmacoeconomic analysis</kwd><kwd>decision-tree</kwd><kwd>Markov model</kwd><kwd>sensitivity analysis</kwd><kwd>hematology</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>клинико-экономический анализ</kwd><kwd>фармакоэкономический анализ</kwd><kwd>древо решений</kwd><kwd>модель Маркова</kwd><kwd>анализ чувствительности</kwd><kwd>гематология</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>American society of hematology: http://www.hematology.org/Clinicians/Drugs/Programs/</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Saret C., Winn A. 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