Pediatric Hematology/Oncology and ImmunopathologyPediatric Hematology/Oncology and ImmunopathologyВопросы гематологии/онкологии и иммунопатологии в педиатрии1726-17082414-9314Fund Doctors, Innovations, Science for Children22910.24287/1726-1708-2019-18-1-81-87CLINICAL OBSERVATIONSКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯPanniculitis-like T-cell lymphoma in childrenПанникулитоподобная Т-клеточная лимфома у детейhttps://orcid.org/0000-0002-5977-3310GarloevaJ. N.ГарлоеваЮ. Н.
Russian Federation

Julia N. Garloeva - MD, resident of haematology, pediatrician.

117997, Moscow, Samory Mashela st., 1

Гарлоева Юлия Надировна - врач-педиатр, клинический ординатор по специальности «гематология».

117997, Москва, ГСП-7, ул. Саморы Машела, 1

juicyjuls25@gmail.comhttps://orcid.org/0000-0003-2294-0821FominyhV. V.ФоминыхВ. В.
Russian Federation

Moscow

Москва

https://orcid.org/0000-0003-0520-5630ShelihovaL. N.ШелиховаЛ. Н.
Russian Federation

Moscow

Москва

https://orcid.org/0000-0003-3664-2876AbramovD. S.АбрамовД. С.
Russian Federation

Moscow

Москва

https://orcid.org/0000-0002-4779-1896MyakovaN. V.МяковаН. В.
Russian Federation

Moscow

Москва

Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России2104201918181872104201921042019Copyright ©; 2019, «D. Rogachev NMRCPHOI»Copyright ©; 2019, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России2019«D. Rogachev NMRCPHOI»ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава Россииhttps://creativecommons.org/licenses/by/4.0https://hemoncim.com/jour/article/view/229

Subcutaneous panniculitis-like T-cell lymphoma is a rare form of peripheral T-cell lymphoma. The frequency of occurrence of this pathology is 1% of all primary T-cell lymphomas of the skin, at that 20% of all population are children and adolescents, in this way, the percentage of occurrence of this type of tumor in the pediatric population is less than 1%. Given the rarity of pathology, there is no single tactic of therapy and an assessment of its effectiveness. This article presents a review of the literature on the description, diagnosis, and treatment of panniculitis-like T-cell lymphoma. It also presents a clinical case of the development of this type of lymphoma in a 3-year-old child, with a progressive course and subsequent HScT from a haploinentical relative donor.

Patient's parents agreed to use personal dats and photos in research and publications.

Подкожная панникулитоподобная Т-клеточная лимфома - редкая форма периферической Т-клеточной лимфомы. Частота встречаемости данной патологии составляет 1% всех первичных Т-клеточных лимфом кожи; при этом 20% общего числа пациентов с этой патологией - дети и подростки, таким образом, процент встречаемости данного типа опухоли в детском возрасте - менее 1%. Учитывая редкость этого заболевания, не существует единой тактики терапии и оценки ее эффективности. В статье представлен обзор литературы, посвященный описанию, диагностике и лечению панникулитоподобной Т-клеточной лимфомы, рассмотрен клинический случай данного типа лимфомы с прогрессирующим течением у ребенка 3 лет, которому в дальнейшем проведена трансплантация гемопоэтических стволовых клеток от гаплосовместимого родственного донора.

Родители пациента дали согласие на использование информации о нем, в том числе фотографий, в научных исследованиях и публикациях.

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