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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">234</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2019-18-1-127-139</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Complications of central venous catheters insertion and exploitation</article-title><trans-title-group xml:lang="ru"><trans-title>Осложнения при постановке и эксплуатации центральных венозных катетеров</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4509-4154</contrib-id><name-alternatives><name xml:lang="en"><surname>Sugak</surname><given-names>A. B.</given-names></name><name xml:lang="ru"><surname>Сугак</surname><given-names>А. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Anna B. Sugak - MD, PhD, doctor of ultrasound diagnostics.</p><p>117997, Moscow, Samory Mashela st., 1</p></bio><bio xml:lang="ru"><p>Сугак Анна Борисовна  - доктор медицинских наук, врач ультразвуковой диагностики, отделение ультразвуковой диагностики.</p><p>117997, Москва, ГСП-7, ул. Саморы Машела, 1</p></bio><email>sugak08@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7945-2565</contrib-id><name-alternatives><name xml:lang="en"><surname>Shchukin</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Щукин</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Konstantinova</surname><given-names>A. N.</given-names></name><name xml:lang="ru"><surname>Константинова</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2348-221X</contrib-id><name-alternatives><name xml:lang="en"><surname>Feoktistova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Феоктистова</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian National Research Medical University named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-04-21" publication-format="electronic"><day>21</day><month>04</month><year>2019</year></pub-date><volume>18</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>127</fpage><lpage>139</lpage><history><date date-type="received" iso-8601-date="2019-04-21"><day>21</day><month>04</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-04-21"><day>21</day><month>04</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/234">https://hemoncim.com/jour/article/view/234</self-uri><abstract xml:lang="en"><p>Central venous catheters (CVC) are commonly used in patients with a number of serious diseases for total parenteral nutrition, chemotherapy, long-term antibiotic therapy, hemodialysis, treatment in intensive care units, regular blood sampling. CVC greatly facilitate the management of such patients and improve their quality of life, however, they can be a source of various complications - venous thrombosis, catheter-associated infections, damage to the adjacent organs. Over the past three decades advances in the venous access devices and visualization technologies has significantly increased the success of the CVC insertions and decreased the frequency of complications. The review highlights the mechanisms of occurrence, clinical manifestations, methods of diagnosis and treatment, and ways of preventing both the most common and some rare complications that may occur during the insertion and exploitation of CVC.</p></abstract><trans-abstract xml:lang="ru"><p>Центральные венозные катетеры (ЦВК) широко используют у пациентов с рядом тяжелых заболеваний для проведения полного парентерального питания, химиотерапии, длительной антибиотикотерапии, гемодиализа, при лечении в отделениях интенсивной терапии, регулярных заборах крови для анализа. ЦВК значительно облегчают медикам ведение таких пациентов и улучшают качество их жизни, однако могут быть источником различных осложнений - венозных тромбозов, катетер-ассоциированных инфекций, повреждений прилежащих органов. В последние три десятилетия благодаря совершенствованию конструкции устройств венозного доступа и прогрессу в области визуализационных технологий значительно увеличилась частота успешных постановок ЦВК и снизилось количество связанных с ними осложнений. В обзоре освещены механизмы возникновения, клинические проявления, методы диагностики и лечения, а также способы предотвращения наиболее часто встречающихся и некоторых редких осложнений, которые могут возникать в процессе постановки и при эксплуатации ЦВК.</p></trans-abstract><kwd-group xml:lang="en"><kwd>central venous catheter</kwd><kwd>complications</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>центральный венозный катетер</kwd><kwd>осложнения</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1.	lanacci L., Piomelli S. Supportive care for children with cancer. Guidelines of the children's cancer study group. Use of venous access lines. Am J Pediatr Hematol Oncol 1984; 6: 227-81.</mixed-citation><mixed-citation xml:lang="ru">lanacci L., Piomelli S. 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