Pediatric Hematology/Oncology and ImmunopathologyPediatric Hematology/Oncology and ImmunopathologyВопросы гематологии/онкологии и иммунопатологии в педиатрии1726-17082414-9314Fund Doctors, Innovations, Science for Children27010.24287/1726-1708-2019-18-3-130-144LITERATURE REVIEWОБЗОР ЛИТЕРАТУРЫA modern view on the complement systemCовременное представление о системе комплементаShakhidzhanovS. S.ШахиджановС. С.
Russian Federation

Soslan S. Shakhidzhanov, scientist

119991, Moscow, Kosygina st., 4

Шахиджанов Сослан Сергеевич, научный сотрудник

119991, Москва, ул. Косыгина, 4

shakhidzhanov.s@yandex.ruFilippovaA. E.ФилипповаА. Е.
Russian Federation

Moscow

Москва

ButilinA. A.БутылинА. А.
Russian Federation

Moscow

Москва

https://orcid.org/0000-0003-3403-181XAtaullakhanovF. I.АтауллахановФ. И.
Russian Federation

Moscow

Москва

 

Center for Theoretical Problems of Physico-chemical Pharmacology, Russian Academy of SciencesФГБУН «Центр теоретических проблем физико-химической фармакологии» РАНLomonosov Moscow State UniversityФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава РоссииMoscow Institute of Physics and Technology (State University)ФГАОУ ВО «Московский физико-технический институт (государственный университет)»130920191831301441309201913092019Copyright ©; 2019, «D. Rogachev NMRCPHOI»Copyright ©; 2019, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России2019«D. Rogachev NMRCPHOI»ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава Россииhttps://creativecommons.org/licenses/by/4.0https://hemoncim.com/jour/article/view/270

Complement is a part of the immune system which provides host cells with protection against pathogen cells and particles. It is activated when a pathogen invasion is detected. The results of numerous investigations have led to growing realization of the important role of this system in maintaining normal organism homeostasis. This review summarizes a modern view on the complement system.

Комплемент представляет собой часть системы иммунитета, обеспечивающую защиту клеток организма от патогенных клеток и частиц. Она запускается при обнаружении вторжения патогенов. Результаты многочисленных исследований привели к осознанию огромной роли этой системы в поддержании нормального функционирования организма. В данном обзоре описано современное представление о работе системы комплемента.

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