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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">577</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2022-21-2-118-121</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Solitary cutaneous mastocytoma on the scalp of a child; a case report and review of literature</article-title><trans-title-group xml:lang="ru"><trans-title>Solitary cutaneous mastocytoma on the scalp of a child; a case report and review of literature</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bahadoram</surname><given-names>M.</given-names></name><address><country country="IR">Iran, Islamic Republic of</country></address><bio><p>Mohammad Bahadoram</p><p>Ahvaz</p></bio><email>mohammadbahadoram@yahoo.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Joonaki</surname><given-names>Y.</given-names></name><address><country country="IR">Iran, Islamic Republic of</country></address><bio><p>Younes Joonaki</p><p>Department of Dermatology</p><p>Ahvaz</p></bio><email>Joonaki.y@ajums.ac.ir</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yaghoobi</surname><given-names>Reza</given-names></name><name xml:lang="ru"><surname>Yaghoobi</surname><given-names>R.</given-names></name></name-alternatives><address><country country="IR">Iran, Islamic Republic of</country></address><bio><p>Reza Yaghoobi</p><p>Department of Dermatology</p><p>Ahvaz</p></bio><email>Yaghoobi-r@ajums.ac.ir</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Mahmoudian-Sani</surname><given-names>M.-R.</given-names></name><address><country country="IR">Iran, Islamic Republic of</country></address><bio><p>Mohammad-Reza Mahmoudian-Sani</p><p>Ahvaz</p></bio><email>mohamadsani495@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Hassanzadeh</surname><given-names>S.</given-names></name><address><country country="IR">Iran, Islamic Republic of</country></address><bio><p>Shakiba Hassanzadeh, MD</p><p>Thalassemia and Hemoglobinopathy Research Center,</p><p>Ahvaz</p></bio><email>shak.hassanzadeh@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Bahadoram</surname><given-names>S.</given-names></name><address><country country="IR">Iran, Islamic Republic of</country></address><bio><p>Sara Bahadoram</p><p>Ahvaz</p></bio><email>sarabahadoram@yahoo.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>Ahvaz Jundishapur University of Medical Sciences</institution></aff><pub-date date-type="pub" iso-8601-date="2022-07-08" publication-format="electronic"><day>08</day><month>07</month><year>2022</year></pub-date><volume>21</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>118</fpage><lpage>121</lpage><history><date date-type="received" iso-8601-date="2022-01-09"><day>09</day><month>01</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-01-12"><day>12</day><month>01</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/577">https://hemoncim.com/jour/article/view/577</self-uri><abstract xml:lang="en"><p>   Mastocytomas are solitary mast cell tumors that are generally seen on the trunk and extremities. Childhood-onset mastocytomas of the scalp are extremely rare. We report a case of a one-and-a-half-year-old toddler boy that presented with a yellow-brown plaque on his scalp. Pathological evaluation s revealed mast cell accumulation in the upper dermis. These cells were uniform with a fried-egg appearance and had visible cytoplasmic granules with Wright-Giemsa staining. This study demonstrates the difficulty of diagnosing soli¬tary mastocytomas as it is a very rare disease and has non-specific clinical findings. In this study, a child with a rare solitary cutaneous mastocytoma on the scalp was evaluated and a review of previous literature was conducted.</p></abstract><trans-abstract xml:lang="ru"><p>   Mastocytomas are solitary mast cell tumors that are generally seen on the trunk and extremities. Childhood-onset mastocytomas of the scalp are extremely rare. We report a case of a one-and-a-half-year-old toddler boy that presented with a yellow-brown plaque on his scalp. Pathological evaluation s revealed mast cell accumulation in the upper dermis. These cells were uniform with a fried-egg appearance and had visible cytoplasmic granules with Wright-Giemsa staining. This study demonstrates the difficulty of diagnosing soli¬tary mastocytomas as it is a very rare disease and has non-specific clinical findings. In this study, a child with a rare solitary cutaneous mastocytoma on the scalp was evaluated and a review of previous literature was conducted.</p></trans-abstract><kwd-group xml:lang="en"><kwd>mastocytoma</kwd><kwd>solitary mastocytoma</kwd><kwd>c-Kit</kwd><kwd>Darier’s sign</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>mastocytoma</kwd><kwd>solitary mastocytoma</kwd><kwd>c-Kit</kwd><kwd>Darier’s sign</kwd></kwd-group><funding-group><funding-statement xml:lang="en">Vice Chancellor for Research Affairs, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran</funding-statement><funding-statement xml:lang="ru">Vice Chancellor for Research Affairs, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Wagner N, Staubach P. Mastocytosis–pathogenesis, clinical manifestation and treatment. 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