Pediatric Hematology/Oncology and ImmunopathologyPediatric Hematology/Oncology and ImmunopathologyВопросы гематологии/онкологии и иммунопатологии в педиатрии1726-17082414-9314Fund Doctors, Innovations, Science for Children6310.24287/1726-1708-2017-16-3-15-22СтатьиMinimally invasive surgery treatment of children with abdominal neuroblastomaМалоинвазивное хирургическое лечение детей с нейробластомой забрюшинной локализацииhttps://orcid.org/0000-0002-1034-673XAndreevE. S.АндреевЕ. С.
Russian Federation

MD, pediatric surgeon, Surgery Department

Russia 117997, Moscow, Samory Mashela st., 1

детский хирург, отделение онкологии и детской хирургии

117997, Москва, ГСП-7, ул. Саморы Машела, 1

andreev.doctor@gmail.comShamanskayaT. V.ШаманскаяТ. В.
Russian Federation
SukhovM. N.СуховМ. Н.
Russian Federation
TalypovS. R.ТалыповС. Р.
Russian Federation
GrachevN. S.ГрачевН. С.
Russian Federation
https://orcid.org/0000-0002-3704-8783KachanovD. Y.КачановД. Ю.
Russian Federation
UskovaN. G.УсковаН. Г.
Russian Federation
https://orcid.org/0000-0001-7317-7104TereshenkoG. V.ТерещенкоГ. В.
Russian Federation
AmosovaA. A.АмосоваА. А.
Russian Federation
OzerovS. S.ОзеровС. С.
Russian Federation
VarfolomeevaS. R.ВарфоломееваС. Р.
Russian Federation
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава РоссииDmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России, Москва10082017163152210082018Copyright ©; 2017, «D. Rogachev NMRCPHOI»Copyright ©; 2017, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России2017«D. Rogachev NMRCPHOI»ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава Россииhttps://creativecommons.org/licenses/by/4.0https://hemoncim.com/jour/article/view/63

Neuroblastoma is the most common extracranial solid tumor of pediatrics, with the most favorable prognosis in children under 1 year. In the Dmitry Rogachev National Research Centre of Pediatric  Hematology, Oncology and Immunology radical endosurgical treatment of the neuroblastoma abdominal  localization received 39 patients. Local relapses were not observed with the median follow-up time of 36  months. Due to the positive results of endosurgical procedures laparoscopic approach may be the procedure of choice for localized forms of abdominal neuroblastoma without image-defined risk factors.

Нейробластома (НБ) - самая частая экстракраниальная опухоль детского возраста. Наиболее благоприятный прогноз имеют пациенты с локализованной стадией заболевания в возрасте до 1 года. В НМИЦ ДГОИ им. Дмитрия Рогачева эндохирургическое лечение в объеме радикального удаления опухоли забрюшинной локализации выполнено 39 больным. С медианой наблюдения 36 месяцев не отмечено ни одного случая развития локального рецидива заболевания. С учетом положительных результатов лапароскопическое удаление опухоли может быть рекомендовано в качестве операции выбора при локализованных формах НБ и отсутствии факторов хирургического риска, по данным визуализационных методов обследования, с учетом четко сформулированных показаний. Ключевые слова: нейробластома, дети, лапароскопия, лапароскопическая адреналэктомия.

children’s tumorsneuroblastomalaparoscopylaparoscopic adrenalectomy in children.нейробластомадетилапароскопиялапароскопическая адреналэктомия1. Brodeur G.M., Castleberry R.P. Neuroblastoma. In: Pizzo, PA.; Poplack, DG., editors. Principles and Practice of Pediatric Oncology. 2. Philadelphia: J. B. Lippincott; 1993. p. 739-67.Brodeur G.M., Castleberry R.P. Neuroblastoma. In: Pizzo, PA.; Poplack, DG., editors. Principles and Practice of Pediatric Oncology. 2. Philadelphia: J. B. Lippincott; 1993. p. 739-67.2. Young J.L., Ries L.G., Silverberg E., et al. Cancerincidence, survival, andmortality for children younger than age 15 years. Cancer 1986; 58: 598-602. [PubMed: 3719551].Young J.L., Ries L.G., Silverberg E., et al. Cancerincidence, survival, andmortality for children younger than age 15 years. Cancer 1986; 58: 598-602. [PubMed: 3719551].3. Look A.T., Hayes F.A., Shuster J.J., et al. Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol 1991; 9: 581-91 [PubMed: 2066755].Look A.T., Hayes F.A., Shuster J.J., et al. Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol 1991; 9: 581-91 [PubMed: 2066755].4. Seeger R.C., Brodeur G.M., Sather H., et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med. 1985; 313: 1111-6 [PubMed: 4047115]Seeger R.C., Brodeur G.M., Sather H., et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med. 1985; 313: 1111-6 [PubMed: 4047115]5. Breslow N., McCann B. Statistical estimation of prognosis for children with neuroblastoma. Cancer Res 1971; 31: 2098-103 [PubMed: 5120301].Breslow N., McCann B. Statistical estimation of prognosis for children with neuroblastoma. Cancer Res 1971; 31: 2098-103 [PubMed: 5120301].6. Colon N.C., Chung D.H. Neuroblastoma. Adv Pediatr 2011; 58 (1): 297-311.Colon N.C., Chung D.H. Neuroblastoma. Adv Pediatr 2011; 58 (1): 297-311.7. Park J.R., Eggert A., Caron H. Neuroblastoma: biology, prognosis, and treatment. Hematol Oncol Clin North Am 2010; 24: 65-86 [PubMed: 20113896].Park J.R., Eggert A., Caron H. Neuroblastoma: biology, prognosis, and treatment. Hematol Oncol Clin North Am 2010; 24: 65-86 [PubMed: 20113896].8. Kiely E. A technique for execision of abdominal and pelvic neuroblastomas. Ann R Coll Surg Engl 2007; 89: 342-8.Kiely E. A technique for execision of abdominal and pelvic neuroblastomas. Ann R Coll Surg Engl 2007; 89: 342-8.9. Davidoff A.M. Neuroblastoma. Semin Pediatr Surg 2012; 21 (1): 2-14.Davidoff A.M. Neuroblastoma. Semin Pediatr Surg 2012; 21 (1): 2-14.10. Douglas R. Outcome After Surgery Alone or With Restricted Use of Chemotherapy for Patients With Low-Risk Neuroblastoma: Results of Children’s Oncology Group Study P9641. J Clin Oncol 2012; 30: 1842-8.Douglas R. Outcome After Surgery Alone or With Restricted Use of Chemotherapy for Patients With Low-Risk Neuroblastoma: Results of Children’s Oncology Group Study P9641. J Clin Oncol 2012; 30: 1842-8.11. Kelleher C.M. Clinical outcomes in children with adrenal neuroblastoma undergoing open versus laparoscopic adrenalectomy. J Pediatr Surg 2013; 48: 1727-32.Kelleher C.M. Clinical outcomes in children with adrenal neuroblastoma undergoing open versus laparoscopic adrenalectomy. J Pediatr Surg 2013; 48: 1727-32.12. Lacreuse I., Stéphane, Valla J. Thoracoscopic resection of neurogenic tumors in children. J Pediatr Surg 2007: 42: 1725-8.Lacreuse I., Stéphane, Valla J. Thoracoscopic resection of neurogenic tumors in children. J Pediatr Surg 2007: 42: 1725-8.13. Iwanaka T., et al. Surgical treatment for abdominal neuroblastoma in the laparoscopic era. Surg Endosc 2001; 15 (7): 751-4.Iwanaka T., et al. Surgical treatment for abdominal neuroblastoma in the laparoscopic era. Surg Endosc 2001; 15 (7): 751-4.14. Yamomoto H. Laparoscopic surgery for neuroblastoma identified by mass screening. J Pediatr Surg 1996; 3 1(3): 385-8.Yamomoto H. Laparoscopic surgery for neuroblastoma identified by mass screening. J Pediatr Surg 1996; 3 1(3): 385-8.15. Shimada H., Umehara S., Monobe Y., et al. International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children’s Cancer Group. Cancer 2001; 92: 2451-61 [PubMed: 11745303].Shimada H., Umehara S., Monobe Y., et al. International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children’s Cancer Group. Cancer 2001; 92: 2451-61 [PubMed: 11745303].16. Hervé J.B., et al. Guidelines for Imaging and Staging of Neuroblastic Tumors: Consensus Report from the International Neuroblastoma Risk Group Project. Radiology 2011; 261 (1): 243-57.Hervé J.B., et al. Guidelines for Imaging and Staging of Neuroblastic Tumors: Consensus Report from the International Neuroblastoma Risk Group Project. Radiology 2011; 261 (1): 243-57.