Pediatric Hematology/Oncology and ImmunopathologyPediatric Hematology/Oncology and ImmunopathologyВопросы гематологии/онкологии и иммунопатологии в педиатрии1726-17082414-9314Fund Doctors, Innovations, Science for Children6510.24287/1726-1708-2017-16-3-28-34СтатьиThe usage of superimposed high-frequency jet ventilation in the treatment of acute respiratory distress syndrome in children with oncohematological diseasesИспользование сочетанной высокочастотной струйной ИВЛ в лечении острого респираторного дистресс-синдрома у детей с онкогематологическими заболеваниямиhttps://orcid.org/0000-0002-4348-4573IvanashkinA. Yu.ИванашкинА. Ю.
Russian Federation

MD, Intensive Care Unit

Russia 117997, Moscow, Samory Mashela st., 1 Tel.: 8(495) 664-7745

врач-анестезиолог-реаниматолог

117997, Москва, ГСП-7, ул. Саморы Машела, 1 Тел.: 8 (495) 664-7745

ivanashkin@mail.ruhttps://orcid.org/0000-0001-8264-2258KhaminI. G.ХаминИ. Г.
Russian Federation
https://orcid.org/0000-0001-9650-7292RybalkoA. S.РыбалкоА. С.
Russian Federation
https://orcid.org/0000-0002-4695-9765SemyonovI. A.СеменовИ. А.
Russian Federation
https://orcid.org/0000-0002-1258-8281PetrovaU. N.ПетроваУ. Н.
Russian Federation
https://orcid.org/0000-0001-8417-3555LazarevV. V.ЛазаревВ. В.
Russian Federation
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России, МоскваNational Scientific and Practical Center of Children’s HealthФГБУ «Национальный научно-практический центр здоровья детей» Минздрава России, МоскваPirogov Russian National Research Medical UniversityФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Москва10082017163283410082018Copyright ©; 2017, «D. Rogachev NMRCPHOI»Copyright ©; 2017, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России2017«D. Rogachev NMRCPHOI»ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава Россииhttps://creativecommons.org/licenses/by/4.0https://hemoncim.com/jour/article/view/65

The treatment of acute respiratory distress syndrome (ARDS) in children with oncohematological diseases remains one of the most difficult problem of the intensive care. The present study was performed to assess  the potential of the usage of superimposed highfrequency jet ventilation (SHFJV) in the treatment of ARDS  in children with oncohematological diseases. High-frequency ventilation was performed with TwinStream™  (Carl Reiner, Austria) apparatus in the superimposed high-frequency jet ventilation mode. 13 cases of ARDS treatment were analysed. High-frequency ventilation was indicated in cases of a confirmed ARDS or the  inefficacy of conventional mechanical ventilation: peak airway pressure (Ppeak) > 30 mm Hg, FiO2 – 100%, SpO2 < 92%, pCO2 > 50 mm Hg. SHFJV was conducted for 2–12 days (5±3 days on average). 10 patients  (76,9%) showed an improvement in lung X-ray, increased levels of РаО2 > 100 mm Hg, РаО2/FiO2 > 200,  a reduced fraction of inspired oxygen (FiO2), the optimization of SHFJV parameters with a subsequent  switch-over to traditional ALV techniques and extubation. Five out of 13 patients died. The first results of  SHFJV application in oncohematological pediatric patients with severe ARDS showed the efficacy of this  alternative method used when adequate gas exchange cannot be achieved with traditional methods of lung ventilation.

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