<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">81</article-id><article-id pub-id-type="doi">10.24287/1726-1708-2017-16-1-54-61</article-id><article-categories><subj-group subj-group-type="toc-heading"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Inflammatory myofibroblastic tumor of the small bowel mesentery complicated by the intestinal obstruction</article-title><trans-title-group xml:lang="ru"><trans-title>Воспалительная миофибробластическая опухоль брыжейки тонкой кишки, осложнившаяся острой кишечной непроходимостью</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kachanov</surname><given-names>D. Yu.</given-names></name><name xml:lang="ru"><surname>Качанов</surname><given-names>Д. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Department of clinical oncology</p><p>Russia 117997, Moscow, Samory Mashela st., 1</p><p> </p></bio><email>kachanov78@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shamanskaya</surname><given-names>T. V.</given-names></name><name xml:lang="ru"><surname>Шаманская</surname><given-names>Т. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Suleymanova</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Сулейманова</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Merkulov</surname><given-names>N. N.</given-names></name><name xml:lang="ru"><surname>Меркулов</surname><given-names>Н. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Feoktistova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Феоктистова</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Talypov</surname><given-names>S. R.</given-names></name><name xml:lang="ru"><surname>Талыпов</surname><given-names>С. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Roschin</surname><given-names>V. Y.</given-names></name><name xml:lang="ru"><surname>Рощин</surname><given-names>В. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shcherbakov</surname><given-names>A. P.</given-names></name><name xml:lang="ru"><surname>Щербаков</surname><given-names>А. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tereschenko</surname><given-names>G. V.</given-names></name><name xml:lang="ru"><surname>Терещенко</surname><given-names>Г. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kazakova</surname><given-names>A. N.</given-names></name><name xml:lang="ru"><surname>Казакова</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Varfolomeeva</surname><given-names>S. R.</given-names></name><name xml:lang="ru"><surname>Варфоломеева</surname><given-names>С. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Research Center of Pediatric Hematology, oncology and Immunology named after Dmitry Rogachev</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный научно-практический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-02-10" publication-format="electronic"><day>10</day><month>02</month><year>2017</year></pub-date><volume>16</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>54</fpage><lpage>61</lpage><history><date date-type="received" iso-8601-date="2018-08-10"><day>10</day><month>08</month><year>2018</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/81">https://hemoncim.com/jour/article/view/81</self-uri><abstract xml:lang="en"><p>Inflammatory myofibroblastic tumor (IMT) is a rare type of neoplasm in pediatric age group with intermediate biologic behaviour. Intestinal obstruction is a rare complication of IMT. The article describes the approaches for differential diagnosis and therapy of patients with intra-abdominal IMT based on the literature review. The case of 5-month-old boy with IMT of the small bowel mesentery is presented.</p></abstract><trans-abstract xml:lang="ru"><p>Воспалительная миофибробластическая опухоль (ВМО) - редкий вид новообразований детского возраста, характеризующийся промежуточным биологическим поведением. Еще реже данная опухоль осложняется кишечной непроходимостью. В статье изложены подходы к дифференциальной диагностике и лечению пациентов с ВМО брюшной полости, основанные на обзоре современной литературы. Приведено описание клинического случая развития острой кишечной непроходимости у ребенка 5 месяцев с ВМО брыжейки кишки. Ключевые слова: дети, воспалительная миофибробластическая опухоль, редкие опухоли, кишечная непроходимость, ALK.</p></trans-abstract><kwd-group xml:lang="en"><kwd>children</kwd><kwd>inflammatory myofibroblastic tumor</kwd><kwd>rare tumor</kwd><kwd>intestinal obstruction</kwd><kwd>ALK.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>воспалительная миофибробластическая опухоль</kwd><kwd>редкие опухоли</kwd><kwd>кишечная непроходимость</kwd><kwd>ALK</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Coffin C.M, Fletcher J.A. Inflammatory myofibroblastic tumour. WHO Classification of Tumours of Soft Tissue and Bone. WHO/IARC Classification of Tumours, 4th Edition, Volume 5. Fletcher C.D.M., Bridge J.A., Hogendoorn P.C.W., Mertens F., eds. Lyon: International Agency for Research on Cancer; 2013:83-86.</mixed-citation><mixed-citation xml:lang="ru">Coffin C.M, Fletcher J.A. Inflammatory myofibroblastic tumour. WHO Classification of Tumours of Soft Tissue and Bone. WHO/IARC Classification of Tumours, 4th Edition, Volume 5. Fletcher C.D.M., Bridge J.A., Hogendoorn P.C.W., Mertens F., eds. Lyon: International Agency for Research on Cancer; 2013:83-86.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Coffin C.M., Watterson J., Priest J.R., Dehner L.P. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995;19(8):859-872.</mixed-citation><mixed-citation xml:lang="ru">Coffin C.M., Watterson J., Priest J.R., Dehner L.P. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995;19(8):859-872.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Качанов Д.Ю., Шаманская Т.В., Добреньков К.В., Варфоломеева С.Р. Воспалительная миофибробластическая опухоль у детей. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2008;7(3):16-20.</mixed-citation><mixed-citation xml:lang="ru">Качанов Д.Ю., Шаманская Т.В., Добреньков К.В., Варфоломеева С.Р. Воспалительная миофибробластическая опухоль у детей. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2008;7(3):16-20.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Ciftci A.O., Akçören Z., Tanyel F.C., Senocak M.E., Cağlar M., Hiçsönmez A. Inflammatory pseudotumor causing intestinal obstruction: diagnostic and therapeutic aspects. J Pediatr Surg. 1998;33(12):1843-1845.</mixed-citation><mixed-citation xml:lang="ru">Ciftci A.O., Akçören Z., Tanyel F.C., Senocak M.E., Cağlar M., Hiçsönmez A. Inflammatory pseudotumor causing intestinal obstruction: diagnostic and therapeutic aspects. J Pediatr Surg. 1998;33(12):1843-1845.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Takahashi T., Okazaki T., Lane GJ, Hayashi T., Arakawa A., Yamataka A. Mesenteric inflammatory pseudo-tumour of the small intestine presenting with intestinal obstruction in a child: case report and literature review. Afr J Paediatr Surg. 2014;11(4):347-350.</mixed-citation><mixed-citation xml:lang="ru">Takahashi T., Okazaki T., Lane GJ, Hayashi T., Arakawa A., Yamataka A. Mesenteric inflammatory pseudo-tumour of the small intestine presenting with intestinal obstruction in a child: case report and literature review. Afr J Paediatr Surg. 2014;11(4):347-350.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Blohm M.E, Vesterling-Hörner D., Calaminus G., Göbel U. Alpha 1-fetoprotein (AFP) reference values in infants up to 2 years of age. Pediatr Hematol Oncol. 1998;15(2):135-142.</mixed-citation><mixed-citation xml:lang="ru">Blohm M.E, Vesterling-Hörner D., Calaminus G., Göbel U. Alpha 1-fetoprotein (AFP) reference values in infants up to 2 years of age. Pediatr Hematol Oncol. 1998;15(2):135-142.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Dalton B.G., Thomas P.G., Sharp N.E., Manalang M.A., Fisher J.E., Moir C.R. et al. Inflammatory myofibroblastic tumors in children. J Pediatr Surg. 2016;51(4):541-544.</mixed-citation><mixed-citation xml:lang="ru">Dalton B.G., Thomas P.G., Sharp N.E., Manalang M.A., Fisher J.E., Moir C.R. et al. Inflammatory myofibroblastic tumors in children. J Pediatr Surg. 2016;51(4):541-544.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Alaggio R., Cecchetto G., Bisogno G., Gambini C., Calabrò M.L., Inserra A. et al. Inflammatory myofibroblastic tumors in childhood: a report from the Italian Cooperative Group studies. Cancer. 2010;116(1):216-226.</mixed-citation><mixed-citation xml:lang="ru">Alaggio R., Cecchetto G., Bisogno G., Gambini C., Calabrò M.L., Inserra A. et al. Inflammatory myofibroblastic tumors in childhood: a report from the Italian Cooperative Group studies. Cancer. 2010;116(1):216-226.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Fisher R.G., Wright P.F., Johnson J.E. Inflammatory pseudotumor presenting as fever of unknown origin. Clin Infect Dis. 1995;21(6):1492-1494.</mixed-citation><mixed-citation xml:lang="ru">Fisher R.G., Wright P.F., Johnson J.E. Inflammatory pseudotumor presenting as fever of unknown origin. Clin Infect Dis. 1995;21(6):1492-1494.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Oeconomopoulou A., de Verney Y., Kanavaki K., Stefanaki K., Pavlakis K., Salakos C. Inflammatory myofibroblastic tumor of the small intestine mimicking acute appendicitis: a case report and review of the literature. J Med Case Rep. 2016;10:100.</mixed-citation><mixed-citation xml:lang="ru">Oeconomopoulou A., de Verney Y., Kanavaki K., Stefanaki K., Pavlakis K., Salakos C. Inflammatory myofibroblastic tumor of the small intestine mimicking acute appendicitis: a case report and review of the literature. J Med Case Rep. 2016;10:100.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Chung E.M., Biko D.M., Arzamendi A.M., Meldrum J.T., Stocker J.T. Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 2015;35(2):521-546.</mixed-citation><mixed-citation xml:lang="ru">Chung E.M., Biko D.M., Arzamendi A.M., Meldrum J.T., Stocker J.T. Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 2015;35(2):521-546.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Cook J.R., Dehner L.P., Collins M.H., Ma Z., Morris S.W., Coffin C.M. et al. Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. Am J Surg Pathol. 2001;25(11):1364-1371.</mixed-citation><mixed-citation xml:lang="ru">Cook J.R., Dehner L.P., Collins M.H., Ma Z., Morris S.W., Coffin C.M. et al. Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. Am J Surg Pathol. 2001;25(11):1364-1371.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Oguz B., Ozcan H.N., Omay B., Ozgen B., Haliloglu M. Imaging of childhood inflammatory myofibroblastic tumor. Pediatr Radiol. 2015;45(11):1672-1681.</mixed-citation><mixed-citation xml:lang="ru">Oguz B., Ozcan H.N., Omay B., Ozgen B., Haliloglu M. Imaging of childhood inflammatory myofibroblastic tumor. Pediatr Radiol. 2015;45(11):1672-1681.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Johnson K., Notrica D.M., Carpentieri D., Jaroszewski D., Henry M.M. Successful treatment of recurrent pediatric inflammatory myofibroblastic tumor in a single patient with a novel chemotherapeutic regimen containing celecoxib. J Pediatr Hematol Oncol. 2013;35(5):414-416.</mixed-citation><mixed-citation xml:lang="ru">Johnson K., Notrica D.M., Carpentieri D., Jaroszewski D., Henry M.M. Successful treatment of recurrent pediatric inflammatory myofibroblastic tumor in a single patient with a novel chemotherapeutic regimen containing celecoxib. J Pediatr Hematol Oncol. 2013;35(5):414-416.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Lovly C.M., Gupta A., Lipson D., Otto G., Brennan T., Chung C.T. et al. Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions. Cancer Discov. 2014;4(8):889-895.</mixed-citation><mixed-citation xml:lang="ru">Lovly C.M., Gupta A., Lipson D., Otto G., Brennan T., Chung C.T. et al. Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions. Cancer Discov. 2014;4(8):889-895.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Antonescu C.R., Suurmeijer A.J., Zhang L., Sung Y.S., Jungbluth A.A., Travis W.D. et al. Molecular characterization of inflam matory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement. Am J Surg Pathol. 2015;39(7):957-967.</mixed-citation><mixed-citation xml:lang="ru">Antonescu C.R., Suurmeijer A.J., Zhang L., Sung Y.S., Jungbluth A.A., Travis W.D. et al. Molecular characterization of inflam matory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement. Am J Surg Pathol. 2015;39(7):957-967.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17. Mossé Y.P., Lim M.S., Voss S.D., Wilner K., Ruffner K., Laliberte J. et al. Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children’s Oncology Group phase 1 consortium study. Lancet Oncol. 2013;14(6):472-480.</mixed-citation><mixed-citation xml:lang="ru">Mossé Y.P., Lim M.S., Voss S.D., Wilner K., Ruffner K., Laliberte J. et al. Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children’s Oncology Group phase 1 consortium study. Lancet Oncol. 2013;14(6):472-480.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
