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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatric Hematology/Oncology and Immunopathology</journal-id><journal-title-group><journal-title xml:lang="en">Pediatric Hematology/Oncology and Immunopathology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы гематологии/онкологии и иммунопатологии в педиатрии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-1708</issn><issn publication-format="electronic">2414-9314</issn><publisher><publisher-name xml:lang="en">Fund Doctors, Innovations, Science for Children</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">943</article-id><article-id pub-id-type="doi">10.24287/1726-1708-943-2151</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Combined reconstruction of the mandible in children using a customized endoprosthesis with a temporomandibular joint implant and fibula free ftap reconstruction</article-title><trans-title-group xml:lang="ru"><trans-title>Комбинированная реконструкция нижней челюсти у детей с использованием индивидуального эндопротеза с искусственным височно-нижнечелюстным суставом и пластикой свободным малоберцовым лоскутом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4451-3233</contrib-id><name-alternatives><name xml:lang="en"><surname>Grachev</surname><given-names>N. S.</given-names></name><name xml:lang="ru"><surname>Грачев</surname><given-names>Н. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Николай Сергеевич Грачев</p><p>Москва</p></bio><email>nick-grachev@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7600-6191</contrib-id><name-alternatives><name xml:lang="en"><surname>Lopatin</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Лопатин</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Андрей Вячеславович Лопатин</p><p>Москва</p></bio><email>and-lopatin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4264-1423</contrib-id><name-alternatives><name xml:lang="en"><surname>Babaskina</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Бабаскина</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Natalya V. Babaskina - a pediatric oncologist at the Department of Pediatric Oncology, Head and Neck Surgery and Neurosurgery.</p><p>1 Samory Mashela St., 117997, Moscow</p></bio><bio xml:lang="ru"><p>Бабаскина Наталья Владимировна - врач-детский онколог отделения детской онкологии, хирургии головы и шеи и нейрохирургии.</p><p>117997, Москва, ул. Саморы Машела, 1</p></bio><email>nbabaskina@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1063-6590</contrib-id><name-alternatives><name xml:lang="en"><surname>Markov</surname><given-names>N. M.</given-names></name><name xml:lang="ru"><surname>Марков</surname><given-names>Н. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Николай Михайлович Марков</p><p>Москва</p></bio><email>markovnm@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3932-6257</contrib-id><name-alternatives><name xml:lang="en"><surname>Vorozhtsov</surname><given-names>I. N.</given-names></name><name xml:lang="ru"><surname>Ворожцов</surname><given-names>И. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Игорь Николаевич Ворожцов</p><p>Москва</p></bio><email>dr.vorozhtsov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4774-5520</contrib-id><name-alternatives><name xml:lang="en"><surname>Starokorova</surname><given-names>K. D.</given-names></name><name xml:lang="ru"><surname>Старокорова</surname><given-names>К. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Капитолина Дмитриевна Старокорова</p><p>Москва</p></bio><email>dr-kapst@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1237-0802</contrib-id><name-alternatives><name xml:lang="en"><surname>Gorokhova</surname><given-names>E. K.</given-names></name><name xml:lang="ru"><surname>Горохова</surname><given-names>Е. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Елизавета Константиновна Горохова</p><p>Москва</p></bio><email>elizavetagorokhova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-7988-2766</contrib-id><name-alternatives><name xml:lang="en"><surname>Veber</surname><given-names>V. P.</given-names></name><name xml:lang="ru"><surname>Вебер</surname><given-names>В. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Вероника Петровна Вебер</p><p>Москва</p></bio><email>veber@logeeks.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-7642-1772</contrib-id><name-alternatives><name xml:lang="en"><surname>Bondar</surname><given-names>M. S.</given-names></name><name xml:lang="ru"><surname>Бондарь</surname><given-names>М. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Матвей Сергеевич Бондарь</p><p>Москва</p></bio><email>dm@logeeks.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-0840-7052</contrib-id><name-alternatives><name xml:lang="en"><surname>Meshcheryakova</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Мещерякова</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>Анастасия Сергеевна Мещерякова</p><p>Москва</p></bio><email>dm@logeeks.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-04-08" publication-format="electronic"><day>08</day><month>04</month><year>2025</year></pub-date><volume>24</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>138</fpage><lpage>143</lpage><history><date date-type="received" iso-8601-date="2025-01-21"><day>21</day><month>01</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-01-22"><day>22</day><month>01</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, «D. Rogachev NMRCPHOI»</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">«D. Rogachev NMRCPHOI»</copyright-holder><copyright-holder xml:lang="ru">ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://hemoncim.com/jour/article/view/943">https://hemoncim.com/jour/article/view/943</self-uri><abstract xml:lang="en"><p>Although surgical removal of head and neck tumors remains a relevant method of local control in pediatric patients, it can lead to the formation of extensive, complex maxillofacial defects. There is no doubt that restoration of anatomical integrity and function of the mandible in children is necessary in the majority of cases, however the choice of reconstruction method is still controversial. In this article, we present a method of combined mandibular reconstruction in children involving the use of a customized endoprosthesis with a temporomandibular joint implant and microsurgical reconstruction with a fibula free flap, which provides optimal functional and aesthetical results and enables patients to receive complete dental rehabilitation in the future (including the placement of permanent dental implants), and report a case series demonstrating this method. The study was approved by the Independent Ethics Committee and the Scientific Council of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation. The patients' parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.</p></abstract><trans-abstract xml:lang="ru"><p>Хирургическое удаление опухолей головы и шеи остается актуальным методом локального контроля новообразований у детей, однако может приводить к формированию объемных смешанных дефектов челюстно-лицевой области. Необходимость восстановления анатомической целостности нижней челюсти и ее функциональной полноценности у детей в большинстве случаев не вызывает сомнений, однако выбор метода реконструкции остается дискутабельным вопросом. В настоящей статье представлен метод выполнения комбинированной реконструкции нижней челюсти у детей с использованием индивидуального эндопротеза с искусственным височно-нижнечелюстным суставом и микрохирургической пластикой свободным малоберцовым лоскутом, который позволяет достичь оптимальных послеоперационных функциональных и эстетических результатов, а также провести в дальнейшем полную стоматологическую реабилитацию, включающую установку постоянных зубных имплантатов. Описана серия случаев применения данного метода. Данное исследование одобрено независимым этическим комитетом и утверждено решением ученого совета ФГБУ «НМИЦ ДГОИ им. Дмитрия Рогачева» Минздрава России. Родители пациентов дали согласие на использование информации, в том числе фотографий детей, в научных исследованиях и публикациях.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pediatric oncology</kwd><kwd>pediatric surgery</kwd><kwd>microsurgery</kwd><kwd>maxillofacial surgery</kwd><kwd>free flap</kwd><kwd>mandible</kwd><kwd>head &amp; neck tumors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>детская онкология</kwd><kwd>детская хирургия</kwd><kwd>микрохирургия</kwd><kwd>челюстно-лицевая хирургия</kwd><kwd>свободный лоскут</kwd><kwd>нижняя челюсть</kwd><kwd>опухоли головы и шеи</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Не указан</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Shahzad F. Pediatric Mandible Reconstruction: Controversies and Considerations. Plast Reconstr Surg Glob Open 2020; 8 (12): e3285. 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