Brentuximab vedotin in therapy of a patient with refractory Hodgkin’s lymphoma and Proteus syndrome

N. V. Myakova; Мякова Наталья Валерьевна; N. V. Smirnova; Смирнова Надежда Владимировна; D. A. Evstratov; Евстратов Дмитрий Андреевич; Yu. G. Abugova; Абугова Юлия Георгиевна; D. N. Balashov; Балашов Дмитрий Николаевич; Yu. Yu. Dyakonova; Дьяконова Юлия Юрьевна; D. M. Konovalov; Коновалов Дмитрий Михайлович; L. A. Potapenko; Потапенко Людмила Арнельевна; Yu. V. Skvortsova; Скворцова Юлия Валериевна; A. A. Maschan; Масчан Алексей Александрович

doi:10.24287/1726-1708-2015-14-2-38-42

Brentuximab vedotin in therapy of a patient with refractory Hodgkin’s lymphoma and Proteus syndrome

Authors: Myakova N.V.¹, Smirnova N.V.¹, Evstratov D.A.¹, Abugova Y.G.¹, Balashov D.N.¹, Dyakonova Y.Y.¹, Konovalov D.M.¹, Potapenko L.A.¹, Skvortsova Y.V.¹, Maschan A.A.¹
Affiliations:
1. Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева
Issue: Vol 14, No 2 (2015)
Pages: 38-42
Section: ЛИМФОМЫ
Submitted: 19.09.2018
Published: 19.05.2015
URL: https://hemoncim.com/jour/article/view/101
DOI: https://doi.org/10.24287/1726-1708-2015-14-2-38-42
ID: 101

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Abstract

Despite the generally favorable prognosis, therapy of patients with refractory Hodgkin's lymphoma remains a great problem today. A clinical case is presented: continuously relapsing Hodgkin's lymphoma in a patient (female) with Proteus syndrome. The patient received several lines of chemotherapy and autologous and then haploidentical hematopoietic stem cell transplantation. In addition to the rare combination of Proteus syndrome and Hodgkin's lymphoma, this case is interesting as it presents brentuximab vedotin as effective third-line therapy.

Keywords

лимфома Ходжкина, синдром Протея, рефрактерность к терапии, брентуксимаб ведотин, Hodgkin’s lymphoma, Proteus syndrome, drug resistance, brentuximab vedotin

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Brentuximab vedotin in therapy of a patient with refractory Hodgkin’s lymphoma and Proteus syndrome

Full Text

Abstract

Keywords

About the authors

References

Supplementary files