Cerebral venous sinus thrombosis and bleeding in the brain in a patient with lymphoblastic lymphoma

D. A. Evstratov; Евстратов Дмитрий Андреевич; P. A. Zharkov; Жарков Павел Александрович; Yu. Yu. Dyakonova; Дьяконова Юлия Юрьевна; Yu. G. Abugova; Абугова Юлия Георгиевна; N. V. Smirnova; Смирнова Надежда Владимировна; V. V. Fominykh; Фоминых Вероника Валерьевна; N. V. Myakova; Мякова Наталья Валерьевна

doi:10.24287/1726-1708-2015-14-2-43-47

Cerebral venous sinus thrombosis and bleeding in the brain in a patient with lymphoblastic lymphoma

Authors: Evstratov D.A.¹, Zharkov P.A.¹, Dyakonova Y.Y.¹, Abugova Y.G.¹, Smirnova N.V.¹, Fominykh V.V.¹, Myakova N.V.¹
Affiliations:
1. Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Issue: Vol 14, No 2 (2015)
Pages: 43-47
Section: ЛИМФОМЫ
Submitted: 19.09.2018
Published: 19.05.2015
URL: https://hemoncim.com/jour/article/view/102
DOI: https://doi.org/10.24287/1726-1708-2015-14-2-43-47
ID: 102

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Abstract

Patients with lymphoblastic lymphomas are effectively treated according to protocols developed by the BFM (Berlin-Frankfurt-Münster) group. Venous sinus thrombosis is a rare complication of therapy for lymphoblastic lymphomas. A clinical case is presented: development of combined thrombohemorrhagic complication in a boy aged 12 years with lymphoblastic lymphoma. The patient received replacement therapy with prothrombin complex factor, antithrombin III, and anticoagulant therapy with high-molecular-weight heparin gradually replaced by low-molecular-weight heparin. Five months of anticoagulant therapy led to complete recanalization of the involved sinuses.

Keywords

дети, лимфобластная лимфома, геморрагический инсульт, тромбоз венозного синуса, L-аспарагиназа, children, lymphoblastic lymphoma, hemorrhagic stroke, venous sinus thrombosis, L-asparaginase

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Cerebral venous sinus thrombosis and bleeding in the brain in a patient with lymphoblastic lymphoma

Full Text

Abstract

Keywords

About the authors

D. A. Evstratov

P. A. Zharkov

Yu. Yu. Dyakonova

Yu. G. Abugova

N. V. Smirnova

V. V. Fominykh

N. V. Myakova

References

Supplementary files