Email this article Childhood acute myeloid leukemia with the t(8;16)(p11;p13) translocation
- Authors: Matveev V.E.1, Kalinina I.I.1, Petrova U.N.1, Dubrovina M.E.1, Starovoitova A.S.2, Maschan A.A.1
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Affiliations:
- Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
- ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России
- Issue: Vol 16, No 4 (2017)
- Pages: 69-74
- Section: Статьи
- Submitted: 09.08.2018
- Published: 09.11.2017
- URL: https://hemoncim.com/jour/article/view/11
- DOI: https://doi.org/10.24287/1726-1708-2017-16-4-69-74
- ID: 11
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Abstract
Acute myeloid leukemia is a clonal systemic disease of the hematologic system, which includes heterogeneous group of diseases. Therefore optimization of methods of treatment of this pathology is an important task. More than 1% of AML with rare translocations can not be strictly divided into risk groups. There are also discrepancies between different researchers’ data on the same cytogenetic abnormalities. In this article we present the experience of diagnostics and therapy of the patient with the rare sub-type of AML with the t(8;16)(p11;p13) translocation in Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology. The patient received high-dose chemotherapy and allogeneic hematopoietic stem cell transplant. According to catamnesis the child (1.5 years) has been in the clinico-hematological and cytogenetic remission.
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About the authors
V. E. Matveev
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Author for correspondence.
Email: matveev-v.e@yandex.ru
ORCID iD: 0000-0002-8709-5238
MD, Department of Hematology
Russia 117997, Moscow, Samory Mashela st., 1
+7 (495) 287-6570, ext. 7433
Russian FederationI. I. Kalinina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-0813-5626
Russian Federation
U. N. Petrova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-1258-8281
Russian Federation
M. E. Dubrovina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0001-8228-4876
Russian Federation
A. S. Starovoitova
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России
ORCID iD: 0000-0002-3115-3427
Russian Federation
A. A. Maschan
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-0016-6698
Russian Federation
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