Email this article Haematologic manifestations of Gaucher’s disease (Review of literature)
- Authors: Smetanina N.S.1,2
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Affiliations:
- Dmitry Rogachev Federal Research Centre of Paediatric Haematology, Oncology and Immunology, Ministry of Health of the Russian Federation
- N.I.Pirogov Russian National Research Medical University
- Issue: Vol 15, No 2 (2016)
- Pages: 53-58
- Section: Статьи
- Submitted: 19.09.2018
- Published: 19.06.2016
- URL: https://hemoncim.com/jour/article/view/162
- DOI: https://doi.org/10.24287/1726-1708-2016-15-2-53-58
- ID: 162
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Abstract
Gaucher's disease is a multisystemic disease developing due to deficiency of glucocerebrosidase and accumulation of glucosylceramide and glucosyl sphingosine in lisosomes of phagocytizing macrophages. A characteristic of all types of Gaucher's disease is given. The review pays a detailed attention to analysis of haematologic manifestations of Gaucher's disease, presents findings of modern research explaining their appearance in this disease.
About the authors
Nataliya S. Smetanina
Dmitry Rogachev Federal Research Centre of Paediatric Haematology, Oncology and Immunology, Ministry of Health of the Russian Federation; N.I.Pirogov Russian National Research Medical University
Author for correspondence.
Email: nataliya.smetanina@fnkc.ru
Russian Federation
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