Bullous epidermolysis after allogeneic stem cells transplantation – non-typical clinical presentation of severe graft versus host disease

M. M. Burgol; Бургол М.М.; D. S. Abramov; Абрамов Д.С.; S. N. Kozlovskaya; Козловская С.Н.; E. M. Khumgaeva; Хумгаева Э.М.; K. V. Mitrakov; Митраков К.В.; I. P. Shiptsina; Шипицына И.П.; D. N. Balashov; Балашов Д.Н.

doi:10.24287/1726-1708-2018-17-2-103-106

Bullous epidermolysis after allogeneic stem cells transplantation – non-typical clinical presentation of severe graft versus host disease

Authors: Burgol M.M.¹, Abramov D.S.¹, Kozlovskaya S.N.¹, Khumgaeva E.M.¹, Mitrakov K.V.¹, Shiptsina I.P.¹, Balashov D.N.¹
Affiliations:
1. Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Issue: Vol 17, No 2 (2018)
Pages: 103-106
Section: CLINICAL OBSERVATIONS
Submitted: 20.09.2018
Published:
URL: https://hemoncim.com/jour/article/view/181
DOI: https://doi.org/10.24287/1726-1708-2018-17-2-103-106
ID: 181

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Abstract

This is a clinical case of bullous epidermolysis, occurred after hematopoietic stem cells transplantation in a patient at high-risk of graft versus host disease. Given the dynamics of disease development, absence of target-organs lesions and specific response to immunosuppressive therapy, we are assuming involvement of additional etiologic factor in the skin damage pathogenesis.