Email this article The use of preventive pleurodesis in patient with Langerhans-cell histiocytosis with lung involvement: the case report and the review
- Authors: Evseev D.A.1, Kalinina I.I.1, Uskova N.G.1, Samarin A.E.1, Raykin E.V.1, Salimova T.Y.1, Baydildina D.D.1, Goronkova O.V.1, Mitrofanova A.M.1, Maschan M.A.1, Maschan A.A.1
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Affiliations:
- Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
- Issue: Vol 17, No 3 (2018)
- Pages: 74-80
- Section: CLINICAL OBSERVATIONS
- Submitted: 24.09.2018
- Accepted: 24.09.2018
- Published: 23.09.2018
- URL: https://hemoncim.com/jour/article/view/194
- DOI: https://doi.org/10.24287/1726-1708-2018-17-3-74-80
- ID: 194
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Abstract
Langerhans-cell histiocytosis (LCH) is a rare myeloid neoplasia (about 3 cases per 1 000 000 children yearly). Lung involvement is rare, usually as a part of multisystem disease. Clinically these lesions manifest with signs of respiratory insufficiency like dyspnea, cough and desaturation. Imaging shows nodules that are gradually transforming into thick- or thin-walled cysts. Rapture of these cysts leads to the pneumothorax which requires drainage. Our report shows clinical case of use of elective pleurodesis to prevent life-threatening complications of histologically confirmed LCH with lung involvement, which can develop either as a result of the disease or due to chemotherapy.
About the authors
D. A. Evseev
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Author for correspondence.
Email: dmitryevseev1991@gmail.com
ORCID iD: 0000-0001-8610-0624
Dmitry A. Evseev, MD, immunologist
117997, Moscow, Samory Mashela st., 1
Russian FederationI. I. Kalinina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-0813-5626
Russian Federation
N. G. Uskova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0001-9424-1646
Russian Federation
A. E. Samarin
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, ImmunologyRussian Federation
E. V. Raykin
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-7634-2053
Russian Federation
T. Yu. Salimova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-2958-1705
Russian Federation
D. D. Baydildina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, ImmunologyRussian Federation
O. V. Goronkova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0001-8571-5395
Russian Federation
A. M. Mitrofanova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, ImmunologyRussian Federation
M. A. Maschan
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0003-1735-0093
Russian Federation
A. A. Maschan
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
ORCID iD: 0000-0002-0016-6698
Russian Federation
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