Email this article Osteosarcoma with lung metastases
- Authors: Zhilkin I.V.1, Akhaladze D.G.1, Litvinov D.V.1, Uskova N.G.1, Tihonova M.V.1, Grachev N.S.1, Karachunskiy A.I.1
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Affiliations:
- Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
- Issue: Vol 18, No 4 (2019)
- Pages: 127-135
- Section: LITERATURE REVIEW
- Submitted: 31.12.2019
- Accepted: 31.12.2019
- Published: 31.12.2019
- URL: https://hemoncim.com/jour/article/view/295
- DOI: https://doi.org/10.24287/1726-1708-2019-18-4-127-135
- ID: 295
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Abstract
Osteosarcoma is the bone tumor that most commonly affects children and adolescents. Before the introduction of polychemotherapy > 90% of patients with osteosarcoma died from pulmonary metastases. Despite development of new protocols of therapy in 30–40% of patients the disease is recurrent, more than 80% of them detected pulmonary metastasis. In this review we discussed the problems of detection of metastatic lung lesions and current approaches of methods of detection and marking of small sized metastatic lung lesions. An additional option in the treatment of lung metastases is intraoperative isolated lung perfusion, surgical approaches of which were also discussed.
About the authors
I. V. Zhilkin
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
Author for correspondence.
Email: izhilkin@gmail.com
ORCID iD: 0000-0002-6922-1077
Correspondence: Ilya V. Zhilkin, МD, pediatrician of Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation.
Address: Russia 117997, Moscow, Samory Mashela st., 1 Russian FederationD. G. Akhaladze
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-1387-209X
Moscow Russian Federation
D. V. Litvinov
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-7461-0050
Moscow Russian Federation
N. G. Uskova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0001-9424-1646
Moscow Russian Federation
M. V. Tihonova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0001-5679-8961
Moscow Russian Federation
N. S. Grachev
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-4451-3233
Moscow Russian Federation
A. I. Karachunskiy
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationMoscow Russian Federation
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