Email this article Prevention and treatment of anemia of prematurity in extremely and very low birth weight infants
- Authors: Sharafutdinova D.R.1, Balashova E.N.1, Pavlovich S.V.2, Kirtbaya A.R.2, Ionov O.V.2, Lenyushkina A.A.1, Zubkov V.V.2, Degtyarev D.N.2
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Affiliations:
- The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatology
- The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatology I.M. Sechenov First Moscow State Medical University
- Issue: Vol 16, No 4 (2017)
- Pages: 13-20
- Section: Статьи
- Submitted: 09.08.2018
- Published: 09.11.2017
- URL: https://hemoncim.com/jour/article/view/3
- DOI: https://doi.org/10.24287/1726-1708-2017-16-4-13-20
- ID: 3
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Abstract
Evaluation and treatment of anemia of prematurity in extremely and very low birth weight infants are presented in this article. Research has been set as a retrospective analysis of 105 infants with anemia of prematurity (in the period from January 2004 to December 2016). This study aimed to analyze the frequency, the volume of red blood cells (RBC) transfusions, the age of the first RBC transfusion and factors associated with RBC transfusions in extremely and very low birth weight preterm infants. A combination of delayed umbilical cord clamping ("milking") and therapy with erythropoietin decrease significantly the frequency of RBC transfusion. There was no significant reduction in the frequency of RBC transfusions in the group of children treated only with erythropoietin, without milking. RBC transfusions increase the risk of bronchopulmonary dysplasia, retinopathy and periventricular leukomalacia. Late therapy with erythropoietin (from 8 days of life) does not increase the risk of developing severe forms of retinopathy of prematurity.
About the authors
D. R. Sharafutdinova
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatology
Email: dikarush@gmail.com
ORCID iD: 0000-0001-9626-5481
graduate student of the Neonatal Intensive Care Unit,
Russia 117997, Moscow, Samory Mashela st., 1
+7 (495) 438-2277
Russian FederationE. N. Balashova
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatology
Email: dikarush@gmail.com
ORCID iD: 0000-0002-3741-0770
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationS. V. Pavlovich
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatologyI.M. Sechenov First Moscow State Medical University
Email: dikarush@gmail.com
ORCID iD: 0000-0002-1313-7079
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationA. R. Kirtbaya
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatologyI.M. Sechenov First Moscow State Medical University
Email: dikarush@gmail.com
ORCID iD: 0000-0002-7628-8157
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationO. V. Ionov
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatologyI.M. Sechenov First Moscow State Medical University
Email: dikarush@gmail.com
ORCID iD: 0000-0002-4153-133X
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationA. A. Lenyushkina
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatology
Email: dikarush@gmail.com
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationV. V. Zubkov
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatologyI.M. Sechenov First Moscow State Medical University
Email: dikarush@gmail.com
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationD. N. Degtyarev
The V.I. Kulakov National medical research center for obstetrics, gynecology and perinatologyI.M. Sechenov First Moscow State Medical University
Author for correspondence.
Email: dikarush@gmail.com
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationReferences
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