Email this article Fisher–Evans syndrome
- Authors: Suntsova E.V.1, Baydildina D.D.1, Kuzminova G.A.1, Kalinina I.I.1, Petrova U.N.1, Salimova T.U.1, Pshonkin A.V.1, Maschan A.A.1, Novichkova G.A.1
-
Affiliations:
- Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
- Issue: Vol 17, No 1 (2018)
- Pages: 75-86
- Section: Статьи
- Submitted: 09.08.2018
- Published: 09.02.2018
- URL: https://hemoncim.com/jour/article/view/30
- DOI: https://doi.org/10.24287/1726-1708-2018-17-1-75-86
- ID: 30
Cite item
Full Text
Abstract
Fisher–Evans syndrome is an uncommon condition characterized by combination of immune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA) with a positive direct Coombs test. ITP and AIHA occur simultaneously or sequentially from several months to years. There is primary (or idiopathic) and secondary (associated with an underlying disease) Fisher–Evans syndrome. Therapeutic approaches in Fisher–Evans syndrome based on ITP and AIHA guidelines, but the results of treatment are variable. Unlike primary ITP and AIHA this syndrome have more severe chronic and relapsing course with significant mortality. In this article we present four clinical cases of sequentially occur of ITP and AIHA, treatments and their outcomes in childhood.
About the authors
E. V. Suntsova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
ORCID iD: 0000-0001-8404-1800
MD, Department of hematopoiesis depressions, myeloid leukemias, rare and inherited diseases
Russia 117997, Moscow, Samory Mashela st., 1
+7 (495) 287-6570, ext. 5567
D. D. Baydildina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
Russian Federation
G. A. Kuzminova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
Russian Federation
I. I. Kalinina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
ORCID iD: 0000-0002-0813-5626
Russian Federation
U. N. Petrova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
ORCID iD: 0000-0002-1258-8281
Russian Federation
T. U. Salimova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
Russian Federation
A. V. Pshonkin
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
ORCID iD: 0000-0002-2057-2036
Russian Federation
A. A. Maschan
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Email: elena.suncova@fcchomoscow.ru
ORCID iD: 0000-0002-0016-6698
Russian Federation
G. A. Novichkova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology
Author for correspondence.
Email: elena.suncova@fcchomoscow.ru
ORCID iD: 0000-0002-2322-5734
Russian Federation
References
Supplementary files
