Atypical aggressive development of pigmented epithelioid melanocytoma in patient with Fanconi Anemia after hematopoietic stem cell transplantation

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Abstract

Pigmented epithelioid melanocytoma (PEM) is an uncommon, recently described melanocytic lesion. There is a high rate of regional metastases, but limited evidence of distant metastases, an indolent clinical course and favorable outcome. The article presents a clinical case of PEM with aggressive behavior and distant metastases in patient with Fanconi Anemia after hematopoietic stem cell transplantation. Parents gave their consent to use information about the child, including fotos, in the article.

About the authors

S. A. Radygina

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

Author for correspondence.
Email: ra-svet-7@yandex.ru
ORCID iD: 0000-0002-7696-1153

Hematologist, Hematopoietic Stem Cell Transplantation Department №2,

Russia, 117997, Moscow, Samory Mashela st., 1

Russian Federation

I. S. Kletskaya

Russian Children’s Clinical Hospital of the N.I. Pirogov Russian National Research Medical University, Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0002-8552-7682
Russian Federation

I. O. Kostareva

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation

Russian Federation

K. V. Mitrakov

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0002-2010-5534
Russian Federation

S. N. Kozlovskaya

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0002-1754-1220
Russian Federation

N. M. Ershov

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0003-2677-367X
Russian Federation

I. P. Shipitsina

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0001-8687-5497
Russian Federation

D. N. Balashov

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0003-2689-0569
Russian Federation

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Copyright (c) 2020 Radygina S.A., Kletskaya I.S., Kostareva I.O., Mitrakov K.V., Kozlovskaya S.N., Ershov N.M., Shipitsina I.P., Balashov D.N.

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