Email this article Ganglioneuroma as the phenomenon of neuroblastoma maturation
- Authors: Babakhanova S.B.1, Kachanov D.Y.1, Shcherbakov A.P.1, Roshchin V.Y.1, Druy A.E.1, Likar Y.N.1, Shamanskaya T.V.1
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Affiliations:
- Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
- Issue: Vol 19, No 4 (2020)
- Pages: 133-142
- Section: CLINICAL OBSERVATIONS
- Submitted: 21.12.2020
- Accepted: 21.12.2020
- Published: 08.07.2025
- URL: https://hemoncim.com/jour/article/view/429
- DOI: https://doi.org/10.24287/1726-1708-2020-19-4-133-142
- ID: 429
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Abstract
Ganglioneuroma (GN) represents a mature, well-differentiated tumor arising from the sympathetic nervous system. Mostly developing de novo, GN can appear during the treatment course of poorly differentiated or undifferentiated tumors of the sympathetic nervous system, such as neuroblastoma, or as a result of their spontaneous maturation. In this article we report three clinical cases of spontaneous and induced maturation of neuroblastoma (primary tumor and metastatic lesion) to GN. Histological verification of long-lasting stable or progressing residual tumor mases in patients with neuroblastoma stratified to the observation group plays a pivotal role as it may significantly affect the treatment course. The patients' parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.
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About the authors
S. B. Babakhanova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: dr.sevil@yandex.ru
ORCID iD: 0000-0002-3864-7403
Sevil B. Babakhanova, Pediatric Oncology Resident
1 Samory Mashela St., Moscow 117997
Russian FederationD. Yu. Kachanov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-3704-8783
Moscow Russian Federation
A. P. Shcherbakov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-8129-0545
Moscow Russian Federation
V. Yu. Roshchin
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-9375-7517
Moscow Russian Federation
A. E. Druy
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-1308-8622
Moscow Russian Federation
Yu. N. Likar
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-6158-2222
Moscow Russian Federation
T. V. Shamanskaya
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-3767-4477
Moscow Russian Federation
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