Granulomatous skin lesion as a manifestation of primary immunodeficiency in children
- Authors: Selezneva O.S.1, Shcherbina A.Y.2
- 
							Affiliations: 
							- Regional children's clinical hospital
- Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
 
- Issue: Vol 19, No 4 (2020): supplement
- Pages: 85-93
- Section: MATERIALS OF THE 3rd WORKING MEETING OF ALLERGISTS-IMMUNOLOGISTS
- Submitted: 10.01.2021
- Accepted: 10.01.2021
- Published: 10.01.2021
- URL: https://hemoncim.com/jour/article/view/450
- DOI: https://doi.org/10.24287/1726-1708-2020-19-4suppl-85-93
- ID: 450
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Abstract
Primary immunodeficiencies (PID) compile a genetically heterogeneous group of more than 400 disorders. Most patients with PID are shown to be highly susceptible to various types of infectious diseases. However, in the past decade, non-infectious complications associated with immune dysregulation and autoimmunity have been increasingly recognized in PID. Patients with PID often have skin manifestations, that allow to suspect the diagnosis of immunodeficiency in early childhood. One of the least studied skin manifestations of PID is granulomatous dermatitis. This manuscript current research on the pathogenesis, methods of diagnosis and therapy of granulomatous dermatitis in patients with various PID. 
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About the authors
O. S. Selezneva
Regional children's clinical hospital
							Author for correspondence.
							Email: Selezneva-doc@mail.ru
				                	ORCID iD: 0000-0003-1907-4168
				                																			                								allergist-immunologist of the department of pediatric hematology and oncology with chemotherapy
339th Strelkovoy Divisii St. 14, Rostov-on-Don 344014, Russia 
				                	Russian Federation													
A. Yu. Shcherbina
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
																		                	ORCID iD: 0000-0002-3113-4939
				                																			                								Moscow 
				                	Russian Federation													
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