Primary myelofibrosis in 15-years old child

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Abstract

Primary Myelofibrosis (PMF) is a rare chronic myeloproliferative disease, resulting from the transformation of cells-predecessors of myelopoiesis with the development of fibrosis bone marrow. PMF is typical for  patients over 50 years and in most cases associated with JAK2 V617F, CALR and MPL mutations. This article presents clinical case of PMF in 15-years old child and provides an overview of the literature.

About the authors

G. N. Gordeeva

National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev

Author for correspondence.

Russia 117997, Moscow, Samory Mashela st., 1

Russian Federation

A. V. Pshonkin

National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev

Email: alexey.pshonkin@gmail.com
ORCID iD: 0000-0002-2057-2036

MD, pediatric hematologist/oncologist, head of the outpatient  department,

Russia 117997, Moscow, Samory Mashela st., 1

Russian Federation

I. V. Serkova

National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev

Russia 117997, Moscow, Samory Mashela st., 1 Russian Federation

D. S. Abramov

National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev

Russia 117997, Moscow, Samory Mashela st., 1 Russian Federation

T. V. Konykhova

National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev

Russia 117997, Moscow, Samory Mashela st., 1 Russian Federation

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Copyright (c) 2017 Gordeeva G.N., Pshonkin A.V., Serkova I.V., Abramov D.S., Konykhova T.V.

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This work is licensed under a Creative Commons Attribution 4.0 International License.