Email this article The use of plerixafor and G-CSF during conditioning for hematopoietic stem cell transplantation in a patient with Wiscott–Aldrich syndrome
- Authors: Balashov D.N.1, Gutovskaya E.I.1, Kozlovskaya S.N.1, Radygina S.A.1, Laberko A.L.1, Maschan A.A.1
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Affiliations:
- Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
- Issue: Vol 16, No 3 (2017)
- Pages: 55-58
- Section: Статьи
- Submitted: 10.08.2018
- Published: 10.08.2017
- URL: https://hemoncim.com/jour/article/view/68
- DOI: https://doi.org/10.24287/1726-1708-2017-16-3-55-58
- ID: 68
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Abstract
High incidence of impaired graft function remains a significant issue in patients with Wiskott–Aldrich Syndrome after hematopoietic stem cell transplantation (HSCT). We report a clinical case of graft rejection and second HSCT with novel alternative approach to the conditioning regimen. We used of G-CSF and plerixafor as additional agents in conditioning regimen for stem cell release and opening of bone marrow niches to improve stem cell engraftment.
About the authors
D. N. Balashov
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
Author for correspondence.
Email: bala8@yandex.ru
ORCID iD: 0000-0003-2689-0569
Head of Hematopoietic Stem Cell Transplantation Department #2
Russia 117997, Moscow, Samory Mashela st., 1
Russian FederationE. I. Gutovskaya
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-3800-8927
Russian Federation
S. N. Kozlovskaya
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-1754-1220
Russian Federation
S. A. Radygina
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-7696-1153
Russian Federation
A. L. Laberko
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-2354-2588
Russian Federation
A. A. Maschan
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-0016-6698
Russian Federation
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