Dynamics of platelet functional activity and hemostatic status in a child with chronic immune thrombocytopenia on romiplostim treatment
- Authors: Suntsova E.V.1, Ignatova A.A.1, Pshonkin A.V.1, Serkova I.V.1, Maschan A.A.1, Novichkova G.A.1, Panteleev M.A.1
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Affiliations:
- Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
- Issue: Vol 16, No 3 (2017)
- Pages: 69-72
- Section: Статьи
- Submitted: 10.08.2018
- Published: 10.08.2017
- URL: https://hemoncim.com/jour/article/view/71
- DOI: https://doi.org/10.24287/1726-1708-2017-16-3-69-72
- ID: 71
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Abstract
Immune thrombocytopenia (ITP) is characterized by changes in both quantity and quality of platelets. As a result, severity of bleeding does not always correllate with the degree of thrombocytopenia, The quality of platelets on treatment becomes difficult to evaluate. The most promising method to investigate quality of platelets in ITP is flow cytometry. Here we describe a clinical case of monitoring of a pediatric ITP patient status on romiplostim treatment for 50 weeks using flow cytometry for platelet functional activity control.
Keywords
About the authors
E. V. Suntsova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0001-8404-1800
Russia 117997, Moscow, Samory Mashela st., 1 Russian Federation
A. A. Ignatova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationRussia 117997, Moscow, Samory Mashela st., 1 Russian Federation
A. V. Pshonkin
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-2057-2036
Russia 117997, Moscow, Samory Mashela st., 1 Russian Federation
I. V. Serkova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationRussia 117997, Moscow, Samory Mashela st., 1 Russian Federation
A. A. Maschan
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian FederationRussia 117997, Moscow, Samory Mashela st., 1 Russian Federation
G. A. Novichkova
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
ORCID iD: 0000-0002-2322-5734
Russia 117997, Moscow, Samory Mashela st., 1 Russian Federation
M. A. Panteleev
Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology, Immunology Ministry of Healthcare of Russian Federation
Author for correspondence.
Email: mapanteleev@yandex.ru
ORCID iD: 0000-0002-8128-7757
PhD, DSc, Head of the Laboratory of cellular hemostasis and trombosis
Russia 117997, Moscow, Samory Mashela st., 1
+7 (495) 287-6570, ext. 6932
Russian FederationReferences
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