The inftuence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment

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Abstract

Local and generalized thrombotic events can affect patient outcomes and quality of life. The purpose of our scoping review was to investigate the influence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment. The search for publications was carried out in December 2023 in the PubMed information system. Two authors independently reviewed the studies and extracted data for analysis. The study included 8 publications out of 654 found. The pediatric cohort in the selected studies was mixed with adult patients. Insufficient information was obtained to carry out a meta-analysis and definitively answer the research question. It seems likely that the anatomical and pathophysiological features of maxillofacial pathology, pharmacological effects of therapy and methods of surgical correction may influence the development and progression of local intravascular coagulopathy. There are no recommendations on the choice of standard or integral hemostasis tests for the diagnosis and monitoring of coagulopathy in this pathology. The use of low-molecular-weight heparins can reduce the clinical manifestations of local intravascular coagulopathy.

About the authors

N. P. Leonov

The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: nikoleonov@ya.ru
ORCID iD: 0000-0002-4364-8937

Nikolay P. Leonov, Cand. Med. Sci., an anesthesiologist – intensivist at the Department of Anesthesiology and Critical Care with Surgical Unit

1 Samory Mashela St., Moscow 117997

Russian Federation

D. E. Pavlova

The Morozov Children's Clinical Hospital of the Department of Health of Moscow

ORCID iD: 0000-0002-9558-4234

Moscow

Russian Federation

P. E. Trakhtman

The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-0231-1617

Moscow

Russian Federation

E. A. Spiridonova

Russian University of Medicine of Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-5230-5725

Moscow

Russian Federation

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Copyright (c) 2024 Leonov N.P., Pavlova D.E., Trakhtman P.E., Spiridonova E.A.

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