Experience and prospects of using intravenous iron preparations in pediatric practice

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Abstract

Iron deficiency anemia has medical and social consequences worldwide, so the treatment of iron deficiency is an important goal. Oral iron therapy may not be optimal in some clinical situations requiring rapid replenishment of iron stores or due to possible ineffectiveness or intolerance. Intravenous iron therapy is an effective method for the treatment of iron deficiency anemia. So far, the use of intravenous iron preparations in pediatric patients has been limited, despite extensive experience of their use in adults and the results of studies conducted with children that have also demonstrated the efficacy and safety of this therapeutic option in pediatric patients. First of all, it is due to concerns about a risk of severe allergic reactions which was quite high in the era of first-generation intravenous iron medicines. The emergence of a new generation of more effective and safer intravenous iron preparations, including high-dose parenteral iron products, makes this type of therapy a promising means of treatment for iron deficiency in children and adolescents.

About the authors

N. V. Inyakova

Clinical Research Center of Hematology, Oncology and Immunology of the I.P. Pavlov Ryazan State Medical University of Ministry of Healthcare of the Russian Federation

Email: inyakova.natalia@yandex.ru
ORCID iD: 0000-0002-4210-3492

Natalia V. Inyakova - Cand. Med. Sci., Head of Day Care Hospital of Clinical Research Center of Hematology, Oncology and Immunology of the I.P. Pavlov Ryazan State Medical University of Ministry of Healthcare RF.

5V Stroiteley St., Ryazan, 390029

Russian Federation

M. A. Lunyakova

Clinical Research Center of Hematology, Oncology and Immunology of the I.P. Pavlov Ryazan State Medical University of Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: mlunyakova@mail.ru
ORCID iD: 0000-0002-4543-2945

Ryazan

Russian Federation

V. G. Demikhov

Clinical Research Center of Hematology, Oncology and Immunology of the I.P. Pavlov Ryazan State Medical University of Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-6120-4678

Ryazan

Russian Federation

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