Email this article ALK-positive anaplastic large cell lymphoma: Diagnosis, clinical manifestation, therapy
- Authors: Abramov D.S.1, Myakova N.V.1
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Affiliations:
- Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
- Issue: Vol 14, No 2 (2015)
- Pages: 12-19
- Section: ЛИМФОМЫ
- Submitted: 19.09.2018
- Published: 19.05.2015
- URL: https://hemoncim.com/jour/article/view/99
- DOI: https://doi.org/10.24287/1726-1708-2015-14-2-12-19
- ID: 99
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Abstract
I Anaplastic large cell lymphomas (ALCL), expressing anaplastic lymphoma kinase (ALK) - ALK-positive ALCL - form a group of malignant tumors of lymphoid origin, responsible for 10-15% of all non-Hodgkin's lymphomas in children. This review presents the morphological, phenotypical, cytogenetic, and clinical characteristics of ALK-positive ALCL and the significance of these characteristics for therapy.
About the authors
D. S. Abramov
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Author for correspondence.
Email: pathmorf@mail.ru
Russian Federation
N. V. Myakova
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Email: nmiakova@mail.ru
Russian Federation
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