Современные направления в исследованиях свертывания крови

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Свертывание крови происходит в условиях ее тока и стазиса, оно задействует компоненты клеточного гемостаза и ферментативные каскады реакций, служит для остановки кровотечений и может приводить к возникновению угрожающих жизни тромбов. Несмотря на то, что полный список белков свертывания сформировался несколько десятилетий назад, за последние годы накопилась многочисленная новая информация о его устройстве и регуляции, что привело к созданию новых методов диагностики его нарушений и способов их коррекции. Врожденные и приобретенные нарушения свертывания крови до сих пор остаются острой клинической проблемой. В данном обзоре показаны современные представления об устройстве и функционировании системы свертывания крови в различных условиях.

Об авторах

А. М. Шибеко

ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН;
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России

Автор, ответственный за переписку.
Email: alshibeko@gmail.com
ORCID iD: 0000-0003-1494-3125

канд. биол. наук, ведущий научный сотрудник лаборатории биофизики,

117997, Москва, ул. Саморы Машела, 1 

Россия

А. Н. Баландина

ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН;
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России

117997, Москва, ул. Саморы Машела, 1 Россия

Н. А. Подоплелова

ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН;
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России

ORCID iD: 0000-0001-8013-1112
117997, Москва, ул. Саморы Машела, 1 Россия

М. А. Пантелеев

ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН;
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России

ORCID iD: 0000-0002-8128-7757
117997, Москва, ул. Саморы Машела, 1 Россия

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