A comparative efficacy and safety of using ferrous and ferric iron preparations for management of iron-deficiency anaemia

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Abstract

Iron-deficiency anaemia (IDA) has been studied well enough. But in clinical practice there are a number of problems related to diagnosis, treatment and prevention of iron deficiency, resulting in a high incidence of IDA and iron deficiency in Russia. One of the problems remains a choice of a medicinal formulation for oral IDA therapy, namely, a comparative efficacy and safety of ferrous (+2) and ferric (+3) iron preparations. Ferrous iron salts have long and often been used in clinical practice. They have a higher bioavailability. But according to literature data, the possibility of development of adverse events in using ferrous iron salt formulations is often higher than when using ferric iron preparations. Analysis of literature data is demonstrable of an equal efficacy of there two groups of iron drugs in patients with IDA.

About the authors

Vyacheslav V. Lebedev

Academician I.P.Pavlov Ryazan State Medical University, Ministry of Health of the Russian Federation

Author for correspondence.
Email: lebedev@hemacenter.org
Russian Federation

Valeriy G. Demikhov

Acad. I.P.Pavlov Ryazan State Medical University

Email: demix777@yandex.ru
Russian Federation

Andrey V. Dmitriev

Acad. I.P.Pavlov Ryazan State Medical University

Email: aakavd@yandex.ru
Russian Federation

Manel Aiari

Acad. I.P.Pavlov Ryazan State Medical University

Email: manoukrasiva@gmail.com
Russian Federation

Maria A. Fomina

Acad. I.P.Pavlov Ryazan State Medical University

Russian Federation

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Copyright (c) 2016 Lebedev V.V., Demikhov V.G., Dmitriev A.V., Aiari M., Fomina M.A.

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