Email this article Analysis of survival and possibility of certain events in patients with acute leucosis
- Authors: Slinin A.S.1, Bydanov O.I.1,2, Karachunskiy A.I.1,3
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Affiliations:
- Dmitry Rogachev Federal Research Centre of Paediatric Haematology, Oncology and Immunology, Ministry of Health of the Russian Federation
- Republican Research and Practical Centre of Paediatric Oncology, Haematology and Immunology, Ministry of Health of the Republic of Belarus
- N.I.Pirogov Russian National Research Medical University
- Issue: Vol 15, No 3 (2016)
- Pages: 34-39
- Section: ONCOLOGY
- Submitted: 19.09.2018
- Published: 19.09.2016
- URL: https://hemoncim.com/jour/article/view/168
- DOI: https://doi.org/10.24287/1726-1708-2016-15-3-34-39
- ID: 168
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Abstract
In clinical practice, the following different types of survival are used to analyze the outcomes of therapy in patients with oncological diseases: event-free survival - eFs, overall survival - OS, and relapse-free survival - RFS. At present, in case of EFS or OS curve construction the Kaplan-Meier method is a classical method for analyzing incomplete observations. But it has serious limitations as a method of RFS analysis. The article demonstrates that for correct analysis of the possibility of some of the competing events competing risks analysis should be used. The article also describes methods of survival analysis that are currently employed with indication of related definitions and formulas.
About the authors
Aleksey S. Slinin
Dmitry Rogachev Federal Research Centre of Paediatric Haematology, Oncology and Immunology, Ministry of Health of the Russian Federation
Author for correspondence.
Email: alekseislinin@gmail.com
Russian Federation
Oleg I. Bydanov
Dmitry Rogachev Federal Research Centre of Paediatric Haematology, Oncology and Immunology, Ministry of Health of the Russian Federation; Republican Research and Practical Centre of Paediatric Oncology, Haematology and Immunology, Ministry of Health of the Republic of Belarus
Email: budanov@oncology.by
Russian Federation
Aleksandr I. Karachunskiy
Dmitry Rogachev Federal Research Centre of Paediatric Haematology, Oncology and Immunology, Ministry of Health of the Russian Federation; N.I.Pirogov Russian National Research Medical University
Email: aikarat@mail.ru
Russian Federation
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