Skin damage after the hematopoietic stem cell transplantation. Literature review

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Abstract

Skin damage after hematopoietic stem cell transplantation (HSCT) is common and important diagnostic and therapeutic problem. The most significant causes of skin lesions in HSCT are drug toxicity, infections, and manifestations of skin acute and chronic “graft versus host” disease. Each of the complications can manifest in various forms, as well as to combine with others, exerting a significant negative effect on the patient’s condition, in severe cases posing a threat to the patient’s life. The article summarizes data on the etiology, features of pathogenesis, clinical forms, the main methods of diagnosis and therapy of the most common skin complications of HSCT.

About the authors

T. Z. Aliev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation

Author for correspondence.
Email: timaliev118@gmail.com
ORCID iD: 0000-0003-1091-1521

Pediatric Oncologist Department of Pediatric Bone Marrow and Hematopoietic Stem Cell Transplantation of the Research Institute of Pediatric Oncology and Hematology,

Russia, 115478, Moscow, Kashirskoe Shosse, 23

Russian Federation

E. B. Machneva

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation; Russian Children’s Clinical Hospital of the N.I. Pirogov Russian National Research Medical University, Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0003-2395-4045
Russian Federation

N. V. Sidorova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0003-3797-5808
Russian Federation

T. S. Belysheva

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0001-5911-553X
Russian Federation

T. T. Valiev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0002-1469-2365
Russian Federation

K. I. Kirgizov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Healthcare of Russian Federation

ORCID iD: 0000-0002-2945-284X
Russian Federation

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Copyright (c) 2020 Aliev T.Z., Machneva E.B., Sidorova N.V., Belysheva T.S., Valiev T.T., Kirgizov K.I.

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