Email this article A case report of pilocytic astrocytoma of the brainstem
- Authors: Merishavyan А.А.1, Papusha L.I.1, Valiakhmetova E.F.1, Druy A.E.1, Yasko L.A.1, Brilliantova V.V.1, Artyomov A.V.1, Karachunsky A.I.1
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Affiliations:
- Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
- Issue: Vol 19, No 4 (2020)
- Pages: 120-124
- Section: CLINICAL OBSERVATIONS
- Submitted: 21.12.2020
- Accepted: 21.12.2020
- Published: 08.07.2025
- URL: https://hemoncim.com/jour/article/view/427
- DOI: https://doi.org/10.24287/1726-1708-2020-19-4-120-124
- ID: 427
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Abstract
Low-grade gliomas (LGGs) of the brainstem are a rare nosological group among brain tumours in children. In most cases, radical resection of the tumours localized in the brainstem is impossible due to the high risk of postoperative neurological complications. Presently, there are no uniform approaches to the management of patients with residual tumours of the brainstem; furthermore, current LGG treatment protocols disregard molecular and genetic features of the tumour. In our article we describe the case of the patient with LGG of the brainstem after the performed biopsy. Despite the large volume of the tumour, we decided to follow the patient over time due to the following factors: verification of the “pilocytic astrocytoma” histological diagnosis, detection of the KIAA1549-BRAF chimeric transcript (a marker of a favourable prognosis), as well as the absence of neurological deficit. According to the neuroimaging data, the child has stable disease for a long period of time. The patients' parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.
About the authors
А. А. Merishavyan
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: merishavyan.artur@yandex.ru
ORCID iD: 0000-0002-5310-5928
Artur A. Merishavyan, a pediatric oncologist at the Hematology/Oncology Isolation Unit
1 Samory Mashela St., Moscow 117997
Russian FederationL. I. Papusha
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-7750-5216
Moscow Russian Federation
E. F. Valiakhmetova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-2977-665X
Moscow Russian Federation
A. E. Druy
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-1308-8622
Moscow Russian Federation
L. A. Yasko
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-3007-3772
Moscow Russian Federation
V. V. Brilliantova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-0079-7761
Moscow Russian Federation
A. V. Artyomov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian FederationMoscow Russian Federation
A. I. Karachunsky
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian FederationMoscow Russian Federation
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