Atypical presentation of bartonellosis with hepatolienal lesions

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Abstract

Cat scratch disease is caused by the gram-negative intracellular bacterium Bartonella henselae (B. henselae). Human infection occurs mainly through cat scratches and bites. In typical cases, the clinical course is presented by a primary affect on the skin and regional lymphadenitis. The atypical presentation of infection can occur with fever, abdominal, ocular and neurological manifestations. A special feature of the abdominal form is the presence of solitary or multiple hypo/anechoic foci of different size and shape in the liver and spleen. B. henselae infection is one of the most common mimics of malignant lymphoma, when the spleen is involved in combination with B symptoms (weight loss, night sweats and prolonged fever). A history of recent contact with cats and diagnostic IgG titers to B. henselae indicate infection. There is no consensus on the choice of antimicrobial drug and the duration of therapy for systemic forms. The article presents its own experience in the diagnosis and treatment of such patients. The patient's parents agreed to use the information, including the child's photo, in scientific research and publications. 

About the authors

M. A. Lunyakova

Reserch center for hematology, oncology and immunology of Ryazan State Medical University named after academician I.P. Pavlov, Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-4543-2945

Ryazan

Russian Federation

V. G. Demikhov

Reserch center for hematology, oncology and immunology of Ryazan State Medical University named after academician I.P. Pavlov, Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: demix777@ya.ru
ORCID iD: 0000-0002-6120-4678

MD., Head of Reserch center,

5B Stroiteley St., Ryazan 390029

Russian Federation

N. V. Inyakova

Reserch center for hematology, oncology and immunology of Ryazan State Medical University named after academician I.P. Pavlov, Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-4210-3492

Ryazan

Russian Federation

E. A. Panina

Reserch center for hematology, oncology and immunology of Ryazan State Medical University named after academician I.P. Pavlov, Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-3778-7519

Ryazan

Russian Federation

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Copyright (c) 2021 Lunyakova M.A., Demikhov V.G., Inyakova N.V., Panina E.A.

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