Email this article Russian recombinant coagulation factors: the technological background and the results of clinical studies
- Authors: Volkova S.A.1, Kudlay D.A.2,3, Bogomolova M.D.1, Sirotkin E.A.1, Sorokina Y.A.1
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Affiliations:
- Privolzhsky Research Medical University of Ministry of Healthcare of the Russian Federation
- I.M. Sechenov First Moscow State Medical University of Ministry of Healthcare of the Russian Federation (Sechenov University)
- JSC GENERIUM
- Issue: Vol 20, No 4 (2021)
- Pages: 209-213
- Section: LITERATURE REVIEW
- Submitted: 22.12.2021
- Accepted: 22.12.2021
- Published: 22.12.2021
- URL: https://hemoncim.com/jour/article/view/575
- DOI: https://doi.org/10.24287/1726-1708-2021-20-4-209-213
- ID: 575
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Abstract
The prolongation of survival and the improvement of quality of life in patients with hemophilia A and B are only possible if hemostatic disorders caused by coagulation factor VIII and IX deficiency are managed effectively. Recombinant coagulation factors are playing an ever-increasing role in the preventive care of affected patients. The development, production and use of domestic recombinant coagulation factors opened up new treatment opportunities and improved access to preventive care for hemophilia patients. The results of clinical studies on the efficacy and safety of the Russian recombinant factors showed that they had similar efficacy and safety compared to the plasma derived clotting factors.
About the authors
S. A. Volkova
Privolzhsky Research Medical University of Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: vsvetl@gmail.com
ORCID iD: 0000-0002-6476-7281
cand. med. sci, an associate professor at the V.G. Vogralik Department of Hospital Therapy and General Medical Practice, Chief Hematologist of the Ministry of Healthcare of the Nizhny Novgorod Region,
18 Verkhnevolzhskaya Embankment, Nizhny Novgorod 603155
Russian FederationD. A. Kudlay
I.M. Sechenov First Moscow State Medical University of Ministry of Healthcare of the Russian Federation (Sechenov University);JSC GENERIUM
ORCID iD: 0000-0003-1878-4467
Moscow
Russian FederationM. D. Bogomolova
Privolzhsky Research Medical University of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-8332-8049
18 Verkhnevolzhskaya Embankment, Nizhny Novgorod 603155
Russian FederationE. A. Sirotkin
Privolzhsky Research Medical University of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-6480-5057
18 Verkhnevolzhskaya Embankment, Nizhny Novgorod 603155
Russian FederationYu. A. Sorokina
Privolzhsky Research Medical University of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-8430-237X
18 Verkhnevolzhskaya Embankment, Nizhny Novgorod 603155
Russian FederationReferences
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