Email this article A clinical case of composite pheochromocytoma in a child and a literature review
- Authors: Sagoyan G.B.1, Suleymanova A.M.1, Sidorov I.V.2, Sardalova S.A.1, Rubanskaya M.V.1, Temnyy A.S.1, Ignatenko O.A.1, Odzharova A.A.1, Konovalov D.M.2, Kosilo O.L.3, Kazantsev A.P.1, Varfolomeeva S.R.1
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Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
- Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
- N.I. Pirogov Russian National Research Medical University of Ministry of Healthcare of the Russian Federation
- Issue: Vol 21, No 4 (2022)
- Pages: 91-98
- Section: CLINICAL OBSERVATIONS
- Submitted: 17.01.2023
- Accepted: 17.01.2023
- Published: 26.12.2022
- URL: https://hemoncim.com/jour/article/view/682
- DOI: https://doi.org/10.24287/1726-1708-2022-21-4-91-98
- ID: 682
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Abstract
Composite pheochromocytoma (CPh) is a rare malignant neoplasm that occurs in different age ranges. The main treatment for pheochromocytoma is a complete surgical removal of the tumor, while in the case of neuroblastoma, risk-adapted therapy is used, depending on the risk group, including chemotherapy, autologous bone marrow transplantation, radiation therapy, immunotherapy and 131I-metaiodbenzylguanidine therapy. Due to the rarity of CPh, there are no standard approaches to systemic therapy. The tactics and extent of treatment are determined according to the predominance of the tumor malignant component. This article presents a rare case of the development of composite pheochromocytoma with poorly differentiated neuroblastoma of the left adrenal gland in a 4-year-old child. The patient’s parents gave consent to the use of their child’s data, including photographs, for research purposes and in publications.
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About the authors
G. B. Sagoyan
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: sagoyan-garik@mail.ru
ORCID iD: 0000-0002-7846-3473
Garik B. Sagoyan, a researcher, a pediatric oncologist at the Research Institute of Pediatric Oncology and Hematology
115478, Moscow, Kashirskoe shosse, 23
Russian FederationA. M. Suleymanova
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-5489-1879
Moscow
Russian FederationI. V. Sidorov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-8578-6572
Moscow
Russian FederationS. A. Sardalova
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-3328-0988
Moscow
Russian FederationM. V. Rubanskaya
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-1016-539X
Moscow
Russian FederationA. S. Temnyy
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-9774-8039
Moscow
Russian FederationO. A. Ignatenko
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-2794-6886
Moscow
Russian FederationA. A. Odzharova
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-3576-6156
Moscow
Russian FederationD. M. Konovalov
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-7732-8184
Moscow
Russian FederationO. L. Kosilo
N.I. Pirogov Russian National Research Medical University of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-3463-3626
Moscow
Russian FederationA. P. Kazantsev
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-7309-1650
Moscow
Russian FederationS. R. Varfolomeeva
N.N. Blokhin National Medical Research Center of Oncology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0001-6131-1783
Moscow
Russian FederationReferences
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