Email this article Diagnostic procedure and choice of treatment of various forms of liver hemangiomas in children
- Authors: Petrushin A.V.1, Mylnikov A.A.2, Garbuzov R.V.3, Narbutov A.G.3, Polyaev A.Y.4, Polyaev Y.A.5
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Affiliations:
- National Reseach Practicle Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry Rogachev
- National Reseach Practicle Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry Rogachev Russian Children’s Clinacal Hospital, Ministry of Health of Russian Federation
- Russian Children’s Clinacal Hospital, Ministry of Health of Russian Federation
- City Clinical Hospital № 4 Moscow City Health Department
- Russian Children’s Clinacal Hospital, Ministry of Health of Russian Federation, Moscow Research Institute of pediatric surgery of Pirogov Russian Research Medical University, Ministry of Health of Russian Federation
- Issue: Vol 16, No 1 (2017)
- Pages: 22-27
- Section: Статьи
- Submitted: 10.08.2018
- Published: 10.02.2017
- URL: https://hemoncim.com/jour/article/view/77
- DOI: https://doi.org/10.24287/1726-1708-2017-16-1-22-27
- ID: 77
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Abstract
Liver tumor can be identified in the child from the first days of life, and sometimes in the prenatal period. It is very important to differentiate hemangiomas from vascular malformations, especially in the first year of life. Total in Russian Children’s Clinacal Hospital and Dmitry Rogachev Federal Research Center of Paediatric Hematology, Oncology and Immunology for the period 2004−2016 were examined and treated 90 children. The main method of diagnosis: MSCT, MRI, Doppler ultrasound, angiography. Focal form revealed in 52 children (58%), multifocal 32 (35%), diffuse 6 patients (7%). Treatment methods include: propranolol therapy, endovascular occlusion and surgery. The choice of method occurred based on the type hemangiomas and age of the patient. Therapy of β-blockers was held 61 (67%) child with various forms of hemangiomas of the liver at the age from 1 month to 1 year 2 months. Endovascular treatment performed 38 patients (42%) between the ages of 3 months to 5 years. Endovascular occlusion is performed using the 3 main types of occlusive materials: beads, cylinders and Gianturko spirals. Surgery performed 17 patients (19%), including 1 patient revealed diffuse, multifocal in 3 and 13 focal form. In the group of drug treatment initial response to therapy of β-blockers was obtained in all patients. In the second group, after performing endovascular occlusion of hemangiomas, the reduction of the size of formations with a reduction of blood flow in them, followed by a gradual devolution of formations was observed in all patients. Today catamnesis is 9 years old, relapse is not revealed. In the group of surgical re-operation was required in any case, the relapse of the pathological process is also not observed. Thus, in patients with hepatic hemangiomas expedient selection of the most conservative and minimally invasive treatment.
About the authors
A. V. Petrushin
National Reseach Practicle Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry Rogachev
Author for correspondence.
Email: pantonu@gmail.com
MD, Head of the Department of Interventional Radiology
Russia 117997, Moscow, Samory Mashela st., 1
Russian Federation
A. A. Mylnikov
National Reseach Practicle Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry RogachevRussian Children’s Clinacal Hospital, Ministry of Health of Russian Federation
Russian Federation
R. V. Garbuzov
Russian Children’s Clinacal Hospital, Ministry of Health of Russian FederationRussian Federation
A. G. Narbutov
Russian Children’s Clinacal Hospital, Ministry of Health of Russian FederationRussian Federation
A. Yu. Polyaev
City Clinical Hospital № 4 Moscow City Health DepartmentRussian Federation
Yu. A. Polyaev
Russian Children’s Clinacal Hospital, Ministry of Health of Russian Federation, MoscowResearch Institute of pediatric surgery of Pirogov Russian Research Medical University, Ministry of Health of Russian Federation
Russian Federation
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