The assessment of the efficacy and safety of the personalized rehabilitation of the second stage using modern methods and technologies in children with primary immunodeficiencies

E. K. Mgdsyan; Мгдсян Э. К.; Yu. A. Rodina; Родина Ю. А.; A. B. Abrosimov; Абросимов А. Б.; E. V. Zhukovskaya; Жуковская Е. В.; A. F. Karelin; Карелин А. Ф.; A. Y. Shcherbina; Щербина А. Ю.; G. A. Novichkova; Новичкова Г. А.

doi:10.24287/1726-1708-2023-22-1-90-98

The assessment of the efficacy and safety of the personalized rehabilitation of the second stage using modern methods and technologies in children with primary immunodeficiencies

Authors: Mgdsyan E.K.¹, Rodina Y.A.¹, Abrosimov A.B.¹^,2, Zhukovskaya E.V.¹^,2, Karelin A.F.¹^,2, Shcherbina A.Y.¹, Novichkova G.A.¹
Affiliations:
1. Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
2. Russkoe Pole Treatment and Rehabilitation Center of Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Issue: Vol 22, No 1 (2023)
Pages: 90-98
Section: ORIGINAL ARTICLES
Submitted: 26.01.2023
Accepted: 30.01.2023
Published: 14.02.2023
URL: https://hemoncim.com/jour/article/view/687
DOI: https://doi.org/10.24287/1726-1708-2023-22-1-90-98
ID: 687

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Abstract

Primary immunodeficiencies (PID) are genetically determined defects of the immune system. Despite significant advances in diagnosis and treatment of this group of disorders, personalized rehabilitation therapy aimed at improving the quality of a patient’s life (QOL) is not standardized. Our study of the rehabilitation effectiveness in a group of PID patients (n = 78; 59 boys and 19 girls), treated at the Russkoe Pole Rehabilitation Center, demonstrated significant improvement of the QOL in all aspects. The total QOL scale score increased from 66.13 to 74.89 points according to a child form and from 65.37 to 70.86 points according to a parent form. The greatest improvement in the QOL was achieved in children under 12 years of age, with an increase in the total scale score from 63.22 to 74.95 points (child form), and from 63.24 to 71.34 points (parent form). Therefore, personalized rehabilitation therapy can improve the QOL of patients with PID and can be applied in various rehabilitation centers. The study was approved by the Independent Ethics Committee and the Scientific Council of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation.

Keywords

rehabilitation, children, primary immunodeficiency, quality of life

About the authors

E. K. Mgdsyan

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation

Author for correspondence.
Email: edmondio100@ya.ru
ORCID iD: 0000-0002-9263-6545

Edmond К. Mgdsyan, a resident

1 Samory Mashela St., Moscow 117997, Russia

Russian Federation

Yu. A. Rodina

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0001-9857-4456

1 Samory Mashela St., Moscow 117997, Russia

Russian Federation

A. B. Abrosimov

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation;
Russkoe Pole Treatment and Rehabilitation Center of Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation

ORCID iD: 0000-0002-0676-6694

1 Samory Mashela St., Moscow 117997, Russia

Russian Federation