Extracorporeal photopheresis: how, why and for whom?
- Authors: Kumukova I.B.1,2, Trakhtman P.E.1, Kurnikova E.E.1
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Affiliations:
- Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
- Kommunarka Multidisciplinary Clinical Center of the Department of Health of Moscow
- Issue: Vol 22, No 2 (2023)
- Pages: 159-165
- Section: LITERATURE REVIEW
- Submitted: 28.11.2022
- Accepted: 24.05.2023
- Published: 08.07.2025
- URL: https://hemoncim.com/jour/article/view/732
- DOI: https://doi.org/10.24287/1726-1708-2023-22-2-159-165
- ID: 732
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Abstract
Extracorporeal photopheresis is a method of cell therapy that was developed and introduced into clinical practice of various specialties over 30 years ago but its mechanism of action, clinical application and the possibility of further modification are still on the minds of scientists around the world. Here we provide a review of the existing literature on the major critical aspects of the extracorporeal photopheresis technology as well as information on possible ways of modifying the method, the current understanding of its mechanism of effectiveness, the use in various diseases and pathological conditions and a list of possible side effects.
About the authors
I. B. Kumukova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation; Kommunarka Multidisciplinary Clinical Center of the Department of Health of Moscow
Author for correspondence.
Email: irina.kumukova@fccho-moscow.ru
ORCID iD: 0000-0002-9881-1041
Irina B. Kumukova, Cand. Med. Sci., researcher, Head of Unit
Department of Treatment and Prophylaxis Optimization for HSCT complications
Transfusion Unit
117997
1 Samory Mashela St.
Moscow
Russian FederationP. E. Trakhtman
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0002-0231-1617
Moscow
Russian FederationE. E. Kurnikova
Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
ORCID iD: 0000-0003-4767-5382
Moscow
Russian FederationReferences
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