Combined reconstruction of the mandible in children using a customized endoprosthesis with a temporomandibular joint implant and fibula free ftap reconstruction
- Authors: Grachev N.S.1, Lopatin A.V.1, Babaskina N.V.1, Markov N.M.1, Vorozhtsov I.N.1, Starokorova K.D.1, Gorokhova E.K.1, Veber V.P.1, Bondar M.S.1, Meshcheryakova A.S.1
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Affiliations:
- The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
- Issue: Vol 24, No 1 (2025)
- Pages: 138-143
- Section: ORIGINAL ARTICLES
- Submitted: 21.01.2025
- Accepted: 22.01.2025
- Published: 08.07.2025
- URL: https://hemoncim.com/jour/article/view/943
- DOI: https://doi.org/10.24287/1726-1708-943-2151
- ID: 943
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Abstract
Although surgical removal of head and neck tumors remains a relevant method of local control in pediatric patients, it can lead to the formation of extensive, complex maxillofacial defects. There is no doubt that restoration of anatomical integrity and function of the mandible in children is necessary in the majority of cases, however the choice of reconstruction method is still controversial. In this article, we present a method of combined mandibular reconstruction in children involving the use of a customized endoprosthesis with a temporomandibular joint implant and microsurgical reconstruction with a fibula free flap, which provides optimal functional and aesthetical results and enables patients to receive complete dental rehabilitation in the future (including the placement of permanent dental implants), and report a case series demonstrating this method. The study was approved by the Independent Ethics Committee and the Scientific Council of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation. The patients' parents gave their consent to the use of their child's data, including photographs, for research purposes and in publications.
About the authors
N. S. Grachev
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: nick-grachev@yandex.ru
ORCID iD: 0000-0002-4451-3233
Moscow
Russian FederationA. V. Lopatin
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: and-lopatin@yandex.ru
ORCID iD: 0000-0001-7600-6191
Moscow
Russian FederationN. V. Babaskina
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: nbabaskina@bk.ru
ORCID iD: 0000-0003-4264-1423
Natalya V. Babaskina - a pediatric oncologist at the Department of Pediatric Oncology, Head and Neck Surgery and Neurosurgery.
1 Samory Mashela St., 117997, Moscow
Russian FederationN. M. Markov
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: markovnm@mail.ru
ORCID iD: 0000-0003-1063-6590
Moscow
Russian FederationI. N. Vorozhtsov
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: dr.vorozhtsov@gmail.com
ORCID iD: 0000-0002-3932-6257
Moscow
Russian FederationK. D. Starokorova
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: dr-kapst@yandex.ru
ORCID iD: 0000-0003-4774-5520
Moscow
Russian FederationE. K. Gorokhova
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: elizavetagorokhova@yandex.ru
ORCID iD: 0000-0003-1237-0802
Moscow
Russian FederationV. P. Veber
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: veber@logeeks.ru
ORCID iD: 0009-0009-7988-2766
Moscow
Russian FederationM. S. Bondar
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: dm@logeeks.ru
ORCID iD: 0009-0008-7642-1772
Moscow
Russian FederationA. S. Meshcheryakova
The Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology of Ministry of Healthcare of the Russian Federation
Email: dm@logeeks.ru
ORCID iD: 0009-0009-0840-7052
Moscow
Russian FederationReferences
- Shahzad F. Pediatric Mandible Reconstruction: Controversies and Considerations. Plast Reconstr Surg Glob Open 2020; 8 (12): e3285. doi: 10.1097/GOX.0000000000003285
- Disa J.J., Cordeiro P.G. Mandible reconstruction with microvascular surgery. Semin Surg Oncol 2000; 19 (3): 226–34. doi: 10.1002/1098-2388(200010/11)19:3<226::aid-ssu4>3.0.co;2-n
- Gileva K.S., Romanova E.M., Verbo E.V., Ovchinnikov I.A., Arutyunov G.R., Allakhverdieva E.Z. Vascularized bone autografts in children. Plastic Surgery and Aesthetic Medicine 2022; (3): 20–30. (In Russ.) 10.17116/plast.hirurgia202203120
- Genden E.M., Buchbinder D., Chaplin J.M., Lueg E., Funk G.F., Urken M.L. Reconstruction of the pediatric maxilla and mandible. Arch Otolaryngol Head Neck Surg 2000; 126: 293–300.
- Smartt J.M. Jr, Low D.W., Bartlett S.P. The pediatric mandible: I. A primer on growth and development. Plast Reconstr Surg 2005; 116: 14e– 23e.
- Dowgierd K., Pokrowiecki R., Wolanski W., Kawlewska E., Kozakiewicz M., Wos J., et al. Analysis of the effects of mandibular reconstruction based on microvascular free flaps after oncological resections in 21 patients, using 3D planning, surgical templates and individual implants. Oral Oncol 2022; 127: 105800. doi: 10.1016/j.oraloncology.2022.105800
- Gorokhova E.K., Babaskina N.V., Grachev N.S., Vorozhtsov I.N., Markov N.M., Krasnov A.S. The use of “growing” endoprostheses in the complex treatment of children with post-resection mandibular defects. Stomatology 2024; 103 (4): 10–9. (In Russ.) doi: 10.17116/sto-mat202410304110
- Grachev N.S., Tereshchuk S.V., Babaskina N.V., Vorozhtsov I.N. Experience of free flap reconstruction in children: 14 clinical cases. Head and Neck. Russian journal 2017; (S1): 121. (In Russ.)
- Landes C., Korzinskas T., Dehner J.F., Santo G., Ghanaati S., Sader R. One-stage microvascular mandible reconstruction and alloplastic TMJ prosthesis. J Craniomaxillofac Surg 2014; 42 (1): 28–34. doi: 10.1016/j.jcms.2013.01.043
- Arcuri F., Innocenti M., Menichini G., Pantani C., Raffaini M. Microvascular reconstruction of the mandible with medial femoral condylar flap for treatment of mandibular non-union. Int J Oral Maxillofac Surg 2022; 51 (2): 175–81. doi: 10.1016/j.ijom.2021.05.007
- Muraev A.A., Guseynov N.A., Tsay P.A., Kibardin I.A., Burenchev D.V., Ivanov S.S., et al. Artificial neural networks in dental and maxillofacial radiology: a review. Clinical Dentistry 2020; 3 (95): 72–80. (In Russ.) doi: 10.37988/1811-153X_2020_3_72
- Genden E.M. Reconstruction of the mandible and the maxilla: the evolution of surgical technique. Arch Facial Plast Surg 2010; 12 (2): 87–90. doi: 10.1001/archfacial.2010.18
- Ostrander B.T., Meller L., Harmon M., Archambault K., Kristallis T., Hammer D., Orosco R.K. Free flap jaw reconstruction with dental implantation: A single-institution experience. Head Neck 2024; 46 (6): 1370–9. doi: 10.1002/hed.27683
- Markov N.M., Grachev N.S., Babaskina N.V., Demenchuk P.A., Vorozhtsov I.N., Dudaeva A.A. Dental rehabilitation in the complex treatment of children and adolescents with maxillofacial neoplasms. Stomatology 2020; 99 (6-2): 44–62. (In Russ.) doi: 10.37988/1811-153X_2020_3_72
- Yang S., Fan H., Du W., Li J., Hu J., Luo E. Overgrowth of costochondral grafts in craniomaxillofacial reconstruction: rare complication and literature review. J Craniomaxillofac Surg 2015; 43 (6): 803–12.
- Guyuron B., Lasa C.I. Jr. Unpredictable growth pattern of costochondral graft. Plast Reconstr Surg 1992; 90: 880–6; discussion 887.
- Troulis M.J., Tayebaty F.T., Papadaki M., Bradford Williams W., Kaban L.B. Condylectomy and costochondral graft reconstruction for treatment of active idiopathic condylar resorption. J Oral Maxillofac Surg 2008; 66: 65–72.
- Nokovitch L., Davrou J., Bidault F., Devauchelle B., Dakpé S., Vacher C. Vascular anatomy of the free fibula flap including the lateral head of the soleus muscle applied to maxillo-mandibular reconstruction. Surg Radiol Anat 2019; 41 (4): 447–54. doi: 10.1007/s00276-018-2166-2
- Kalakutsky N.V., Yakunin S.I., Avramenko V.V., Veselova K.A. Assessment of lower limb function after vascularized fibular autografting for the reconstruction of mandibular defects in children. Annals of plastic, reconstructive and aesthetic surgery 2016; (3): 27–34. (In Russ.)
- Barla M., Polirsztok E., Peltié E., Jouve J.L., Legré R., Dautel G., et al. Free vascularised fibular flap harvesting in children: An analysis of donor-site morbidity. Orthop Traumatol Surg Res 2017; 103 (7): 1109–13. doi: 10.1016/j.otsr.2017.05.009
- Valandhan Vedha G., Gopalakrishnan S., Kumar S.J., Menon G.P. Post-operative Complication at the Donor Site of Fibular Free Flap in a Pediatric Patient. Cureus 2022; 14 (1): e21182. doi: 10.7759/cureus.21182
- Grachev N.S., Tereshchuk S.V., Babaskina N.V., Vorozhtsov I.N. Experience of head and neck free flap reconstruction in children. Almanac of Clinical Medicine 45 (6): 518–24. (In Russ.)
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